HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 464 Hs			1 504
+	Hs
		348226 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		379688 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Mm
		348444 MYC_MOUSE (5-463): 1.09e-71: 235: 33.95		FBXW7_MOUSE (88-458): 9.24e-74: 248: 18.06
+	Hs
		379701 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		347517 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		379200 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		347550 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		346159 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		LIS1_HUMAN (302-504): 3.93e-56: 194: 19.11
+	Hs
		196936 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84
+	Hs
		738987 SRBP1_HUMAN (86-464): 8.15e-36: 143: 14.25		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		346404 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Mm
		1112323 SRBP2_MOUSE (138-459): 1.79e-31: 130: 15.11		FBXW7_MOUSE (88-458): 9.24e-74: 248: 18.06
+	Mm
		1257396 SRBP1_MOUSE (91-464): 8.46e-31: 128: 16.80		FBXW7_MOUSE (88-458): 9.24e-74: 248: 18.06
+	Hs
		348035 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86
+	Hs
		898168 MAX_HUMAN (363-463): 2.41e-25: 103: 33.65		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		607803 USF1_HUMAN (184-463): 1.05e-29: 119: 17.83		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Mm
		659344 MAX_MOUSE (363-463): 6.87e-26: 104: 33.65		WDR5_MOUSE (93-333): 2.8e-41: 152: 15.48
+	Hs
		898091 MAX_HUMAN (363-463): 2.41e-25: 103: 33.65		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Dm
		1180744 MYC_DROME (210-462): 2.89e-27: 117: 17.12		Q7KLW9_DROME (26-336): 2.38e-31: 128: 13.52