HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 464 Hs			1 482
+	Hs
		348232 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		379362 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		346694 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		379434 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43
+	Hs
		379392 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		SAFB2_HUMAN (141-482): 1.89e-41: 160: 14.69
+	Hs
		867095 SC24C_HUMAN (17-348): 1.44e-32: 133: 16.29		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		346856 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43
+	Hs
		346757 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		SAFB2_HUMAN (141-482): 1.89e-41: 160: 14.69
+	Dm
		1365681 MYC_DROME (210-462): 2.89e-27: 117: 17.12		Q9VFT4_DROME (169-440): 9.35e-17: 85: 22.62