Protein: ITAV
Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]

Gene: ITAV, ITGAV
Organism: Homo sapiens
Interactions: 153
UniProt ID: P06756

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001570 - vasculogenesis
GO:0001618 - virus receptor activity
GO:0001846 - opsonin binding
GO:0001968 - fibronectin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396549

ITB3
Integrin beta-3

9

20

Small-scale

0.969

High

419160

ITB8
Integrin beta-8

3

20

Small-scale

0.814

High

419153

ITB6
Integrin beta-6

2

20

Small-scale

0.812

High

419152

ITB5
Integrin beta-5

2

20

Small-scale

0.789

High

403733

ITB1
Integrin beta-1

2

20

Small-scale

0.768

High

419210

SUSD4
Sushi domain-containing protein 4

3

3

High-throughput

0.667

High

419235

DPEP2
Dipeptidase 2

3

0

High-throughput

0.638

High

419181

DEF1
Neutrophil defensin 1

2

2

High-throughput

0.628

High

419193

NAAA
N-acylethanolamine-hydrolyzing acid amidase

2

3

High-throughput

0.628

High

419200

SIA4A
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

2

4

High-throughput

0.628

High

419203

PTC1
Protein patched homolog 1

2

5

High-throughput

0.628

High

419219

TMM25
Transmembrane protein 25

2

2

High-throughput

0.628

High

419228

GGH
Gamma-glutamyl hydrolase

2

2

High-throughput

0.628

High

419248

TN13B
Tumor necrosis factor ligand superfamily member 13B

2

1

High-throughput

0.628

High

362692

FINC
Fibronectin

2

6

Small-scale

0.611

High

419205

TAZ
Tafazzin

3

3

High-throughput

0.609

High

419234

FUT8
Alpha-(1,6)-fucosyltransferase

2

0

High-throughput

0.602

High

372976

VTNC
Vitronectin

2

5

Small-scale

0.595

High

419175

PAXI
Paxillin

2

10

Small-scale

0.595

High

419136

MMP2
72 kDa type IV collagenase

2

11

Small-scale

0.584

High

419158

PTPRZ
Receptor-type tyrosine-protein phosphatase zeta

2

8

Small-scale

0.584

High

419195

FAK1
Focal adhesion kinase 1

2

7

Small-scale

0.584

High

419240

FBX6
F-box only protein 6

2

11

High-throughput

0.584

High

419226

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

4

High-throughput

0.574

High

419161

MK03
Mitogen-activated protein kinase 3

1

3

Small-scale

0.561

High

158887

NCTR3
Natural cytotoxicity triggering receptor 3

1

1

High-throughput

0.536

High

216374

EDIL3
EGF-like repeat and discoidin I-like domain-containing protein 3

1

3

High-throughput

0.536

High

318342

ECEL1
Endothelin-converting enzyme-like 1

1

1

High-throughput

0.536

High

328248

BY55
CD160 antigen

1

4

High-throughput

0.536

High

419138

LEG1
Galectin-1

1

20

High-throughput

0.536

High

419146

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

419147

PRG2
Bone marrow proteoglycan

1

3

High-throughput

0.536

High

419162

CALX
Calnexin

1

5

High-throughput

0.536

High

419166

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

6

High-throughput

0.536

High

419197

MFGM
Lactadherin

1

3

High-throughput

0.536

High

419206

CL12B
C-type lectin domain family 12 member B

1

4

High-throughput

0.536

High

419209

LY65C
Lymphocyte antigen 6 complex locus protein G5c

1

1

High-throughput

0.536

High

419213

BRID5
BRICHOS domain-containing protein 5

1

4

High-throughput

0.536

High

419222

CLC4F
C-type lectin domain family 4 member F

1

5

High-throughput

0.536

High

419229

T106A
Transmembrane protein 106A

1

5

High-throughput

0.536

High

419246

BTNL2
Butyrophilin-like protein 2

1

11

High-throughput

0.536

High

419247

FBX2
F-box only protein 2

1

11

High-throughput

0.536

High

419249

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

2

High-throughput

0.536

High

177789

TMPS2
Transmembrane protease serine 2

1

10

High-throughput

0.515

High

419241

TMPS4
Transmembrane protease serine 4

1

10

High-throughput

0.515

High

419151

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

High-throughput

0.515

High

419168

TGFR2
TGF-beta receptor type-2

1

4

High-throughput

0.515

High

419179

RD23A
UV excision repair protein RAD23 homolog A

1

3

High-throughput

0.515

High

201510

DHH
Desert hedgehog protein

1

0

High-throughput

0.513

High

419140

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.513

High

134572

CCN1
CCN family member 1

1

1

Small-scale

0.501

High

419139

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

419144

COBA1

1

5

Small-scale

0.501

High

419145

CO6A1

1

5

Small-scale

0.501

High

419148

PA2GA
Phospholipase A2, membrane associated

1

1

Small-scale

0.501

High

419156

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

2

Small-scale

0.501

High

419167

L1CAM
Neural cell adhesion molecule L1

1

1

Small-scale

0.501

High

419169

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

7

Small-scale

0.501

High

419174

CCN3
CCN family member 3

1

1

Small-scale

0.501

High

419196

LG3BP
Galectin-3-binding protein

1

2

Small-scale

0.501

High

411270

INSR
Insulin receptor

1

6

High-throughput

0.500

High

419134

IGF1R
Insulin-like growth factor 1 receptor

1

5

High-throughput

0.500

High

419208

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

0

High-throughput

0.493

High

319489

LY86
Lymphocyte antigen 86

1

2

High-throughput

0.489

High

362446

C1QA
Complement C1q subcomponent subunit A

1

3

High-throughput

0.489

High

419143

PSPC
Surfactant protein C

1

5

High-throughput

0.489

High

419207

DB136
Defensin beta 136

1

1

High-throughput

0.489

High

419224

CA054
Uncharacterized protein C1orf54

1

4

High-throughput

0.489

High

419225

LCN9
Epididymal-specific lipocalin-9

1

5

High-throughput

0.489

High

419237

CST9L
Cystatin-9-like

1

4

High-throughput

0.489

High

419244

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

2

High-throughput

0.489

High

419252

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

5

Small-scale

0.481

High

419141

OSTP
Osteopontin

1

0

Small-scale

0.480

High

120277

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

121078

LEG8
Galectin-8

1

20

Small-scale

0.479

High

146094

PLPP3
Phospholipid phosphatase 3

1

1

Small-scale

0.479

High

163727

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.479

High

168287

ANGP2
Angiopoietin-2

1

5

Small-scale

0.479

High

204930

TGON2
Trans-Golgi network integral membrane protein 2

1

9

High-throughput

0.479

High

252734

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

1

8

High-throughput

0.479

High

261375

NCOR1
Nuclear receptor corepressor 1

1

4

Small-scale

0.479

High

337777

EGFR
Epidermal growth factor receptor

1

11

High-throughput

0.479

High

373530

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

380895

VWF
von Willebrand factor

1

6

Small-scale

0.479

High

383532

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

9

Small-scale

0.479

High

384102

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

419132

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

7

Small-scale

0.479

High

419133

TSP1
Thrombospondin-1

1

2

Small-scale

0.479

High

419135

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

419137

MET
Hepatocyte growth factor receptor

1

5

Small-scale

0.479

High

419142

LAMP1
Lysosome-associated membrane glycoprotein 1

1

5

High-throughput

0.479

High

419149

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

419150

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

419154

NUCL
Nucleolin

1

4

Small-scale

0.479

High

419155

PTN
Pleiotrophin

1

1

Small-scale

0.479

High

419157

CBL
E3 ubiquitin-protein ligase CBL

1

5

Small-scale

0.479

High

419163

MK01
Mitogen-activated protein kinase 1

1

3

Small-scale

0.479

High

419164

EPHA2
Ephrin type-A receptor 2

1

7

Small-scale

0.479

High

419165

SHC1
SHC-transforming protein 1

1

4

Small-scale

0.479

High

419171

MUC18
Cell surface glycoprotein MUC18

1

3

High-throughput

0.479

High

419177

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.479

High

419178

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

419180

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

4

Small-scale

0.479

High

419184

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

419185

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

419186

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

419187

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

419188

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

419189

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

419191

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

419192

CO4A3
Collagen alpha-3(IV) chain

1

5

Small-scale

0.479

High

419194

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

419199

EP300
Histone acetyltransferase p300

1

3

Small-scale

0.479

High

419201

ILK
Integrin-linked protein kinase

1

2

Small-scale

0.479

High

419202

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

4

Small-scale

0.479

High

419204

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

419211

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

419215

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

419217

TM11B
Transmembrane protease serine 11B

1

10

High-throughput

0.479

High

419218

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

5

Small-scale

0.479

High

419220

PLD3
5'-3' exonuclease PLD3

1

3

High-throughput

0.479

High

419227

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

419230

PLD4
5'-3' exonuclease PLD4

1

3

High-throughput

0.479

High

419232

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.479

High

419236

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

419238

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

419239

ST7
Suppressor of tumorigenicity 7 protein

1

2

High-throughput

0.479

High

419242

T106B
Transmembrane protein 106B

1

5

High-throughput

0.479

High

419245

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

419251

NCOR2
Nuclear receptor corepressor 2

1

3

Small-scale

0.479

High

419176

SERPH
Serpin H1

1

4

High-throughput

0.470

High

330816

PAK4
Serine/threonine-protein kinase PAK 4

1

0

Small-scale

0.458

High

419159

IL32
Interleukin-32

1

0

Small-scale

0.458

High

419170

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.458

High

419172

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

1

0

Small-scale

0.458

High

419173

SDF1
Stromal cell-derived factor 1

1

0

Small-scale

0.458

High

419183

MYPR
Myelin proteolipid protein

1

0

Small-scale

0.458

High

419221

CUL9
Cullin-9

1

0

High-throughput

0.458

High

419223

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.458

High

419233

GDAH
Guanidino acid hydrolase, mitochondrial

1

0

High-throughput

0.458

High

209207

PSCA
Prostate stem cell antigen

1

4

High-throughput

0.445

High

419182

CD81
CD81 antigen

1

20

High-throughput

0.445

High

419190

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

419212

SG11A
Sperm-associated antigen 11A

1

1

High-throughput

0.437

High

419214

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

419243

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.437

High

2085

TVA20
T cell receptor alpha variable 20

1

2

High-throughput

0.407

High

92665

E9PNY5
Low affinity immunoglobulin gamma Fc region receptor III-A

1

3

High-throughput

0.407

High

419198

SG11B
Sperm-associated antigen 11B

1

1

High-throughput

0.407

High

419216

LYZL2
Lysozyme-like protein 2

2

0

High-throughput

0.328

High

419250

INSL5
Insulin-like peptide INSL5

2

0

High-throughput

0.328

High

419231

TECT2
Tectonic-2

1

0

High-throughput

0.279

Low

352860

IFNB
Interferon beta

1

0

Small-scale

0.261

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024