HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: TRRAP (Q9Y4A5)
Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)
Gene: TRRAP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17704800, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 464 Hs			1 3859
+	Hs
		348334 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		739001 SRBP1_HUMAN (86-464): 8.15e-36: 143: 14.25		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		519743 MYCL_HUMAN (19-463): 1.22e-34: 134: 25.28		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		1016119 SRBP2_HUMAN (124-459): 1.17e-30: 128: 14.12		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		607852 USF1_HUMAN (184-463): 1.05e-29: 119: 17.83		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		898224 MAX_HUMAN (363-463): 2.41e-25: 103: 33.65		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Mm
		348435 MYC_MOUSE (5-463): 1.09e-71: 235: 33.95		TRRAP_MOUSE (1292-3859): 0: 2711: 96.48
+	Mm
		659348 MAX_MOUSE (363-463): 6.87e-26: 104: 33.65		TRRAP_MOUSE (1292-3859): 0: 2711: 96.48
+	Hs
		346698 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		ATM_HUMAN (2081-3858): 0: 1072: 12.80
+	Hs
		379271 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		PRKDC_HUMAN (1935-3859): 0: 960: 12.88
+	Hs
		738963 SRBP1_HUMAN (86-464): 8.15e-36: 143: 14.25		ATM_HUMAN (2081-3858): 0: 1072: 12.80
+	Hs
		346497 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		PRKDC_HUMAN (1935-3859): 0: 960: 12.88
+	Mm
		1103464 MLXIP_MOUSE (10-458): 3.57e-46: 173: 16.22		MTOR_MOUSE (2163-3858): 0: 980: 14.80
+	Hs
		787572 MLXIP_HUMAN (10-458): 2.86e-41: 159: 13.99		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		787575 MLXPL_HUMAN (20-459): 2.62e-34: 138: 15.30		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		607807 USF1_HUMAN (184-463): 1.05e-29: 119: 17.83		PRKDC_HUMAN (1935-3859): 0: 960: 12.88