Protein: HEAT6
HEAT repeat-containing protein 6 (Amplified in breast cancer protein 1)

Gene: HEAT6, HEATR6
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q6AI08

Gene Ontology (top 5):
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

774415

BASI
Basigin

3

1

High-throughput

0.609

High

1101271

SLAF1
Signaling lymphocytic activation molecule

2

2

High-throughput

0.558

High

1230758

CD244
Natural killer cell receptor 2B4

2

2

High-throughput

0.558

High

1230759

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

2

1

High-throughput

0.558

High

1230768

VSIG4
V-set and immunoglobulin domain-containing protein 4

2

1

High-throughput

0.549

High

854109

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

380065

HLAB
HLA class I histocompatibility antigen, B alpha chain

2

1

High-throughput

0.504

High

240194

KLK8
Kallikrein-8

1

1

High-throughput

0.489

High

380636

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

2

High-throughput

0.489

High

520881

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

1

High-throughput

0.489

High

634766

GRAH
Granzyme H

1

1

High-throughput

0.489

High

688574

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

3

High-throughput

0.489

High

1090095

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

3

High-throughput

0.489

High

1098902

KLRD1
Natural killer cells antigen CD94

1

3

High-throughput

0.489

High

1156973

NTRK3
NT-3 growth factor receptor

1

1

High-throughput

0.489

High

1230767

CLC2D
C-type lectin domain family 2 member D

1

2

High-throughput

0.489

High

1230771

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.489

High

1230772

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

840734

RS27
Small ribosomal subunit protein eS27

1

0

High-throughput

0.458

High

412090

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

262247

SCN2B
Sodium channel regulatory subunit beta-2

1

1

High-throughput

0.407

High

1230747

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

1

High-throughput

0.407

High

1230755

SNX21
Sorting nexin-21

3

0

High-throughput

0.345

High

427904

ICAM1
Intercellular adhesion molecule 1

2

0

High-throughput

0.328

High

760452

SDC2
Syndecan-2

2

0

High-throughput

0.328

High

821731

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.328

High

1230754

GLMP
Glycosylated lysosomal membrane protein

2

0

High-throughput

0.328

High

1230770

AAKB1
5'-AMP-activated protein kinase subunit beta-1

2

0

High-throughput

0.328

High

1230763

SACA1
Sperm acrosome membrane-associated protein 1

2

0

High-throughput

0.318

High

139237

UPK2
Uroplakin-2

2

0

High-throughput

0.313

High

333047

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

0

High-throughput

0.313

High

388221

GLPA
Glycophorin-A

2

0

High-throughput

0.313

High

1230753

HUMMR
Protein MGARP

2

0

High-throughput

0.313

High

943584

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

0

High-throughput

0.282

High

124377

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.279

Low

182585

GP182
G-protein coupled receptor 182

1

0

High-throughput

0.279

Low

192097

PA2GX
Group 10 secretory phospholipase A2

1

0

High-throughput

0.279

Low

230971

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.279

Low

253441

CST8
Cystatin-8

1

0

High-throughput

0.279

Low

260885

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

291813

STK16
Serine/threonine-protein kinase 16

1

0

High-throughput

0.279

Low

348559

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.279

Low

355000

CHK2
Serine/threonine-protein kinase Chk2

1

0

High-throughput

0.279

Low

374680

RASH
GTPase HRas

1

0

High-throughput

0.279

Low

377891

TNFB
Lymphotoxin-alpha

1

0

High-throughput

0.279

Low

407184

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.279

Low

486574

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.279

Low

574051

HXB1
Homeobox protein Hox-B1

1

0

High-throughput

0.279

Low

783600

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

0

High-throughput

0.279

Low

847779

SSRB
Translocon-associated protein subunit beta

1

0

High-throughput

0.279

Low

922262

LIMK1
LIM domain kinase 1

1

0

High-throughput

0.279

Low

1086012

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.279

Low

1098713

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.279

Low

1129239

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

High-throughput

0.279

Low

1142494

PDCD1
Programmed cell death protein 1

1

0

High-throughput

0.279

Low

1217411

OBSCN
Obscurin

1

0

High-throughput

0.279

Low

1230748

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1230749

IQCF1
IQ domain-containing protein F1

1

0

High-throughput

0.279

Low

1230750

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.279

Low

1230751

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.279

Low

1230752

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1230757

OPALI
Opalin

1

0

High-throughput

0.279

Low

1230760

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

0

High-throughput

0.279

Low

1230762

PGES2
Prostaglandin E synthase 2

1

0

High-throughput

0.279

Low

1230766

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1230769

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.279

Low

293841

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

535178

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.249

Low

630295

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.249

Low

830911

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

1106575

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.249

Low

1113381

CUL3
Cullin-3

1

0

High-throughput

0.249

Low

1230743

LRC31
Leucine-rich repeat-containing protein 31

1

0

High-throughput

0.249

Low

1230745

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1230756

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

1230761

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

171481

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.232

Low

379529

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.232

Low

538769

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

0

High-throughput

0.232

Low

679349

DNJB2
DnaJ homolog subfamily B member 2

1

0

High-throughput

0.232

Low

754043

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.232

Low

1010931

BAT1
b(0,+)-type amino acid transporter 1

1

0

High-throughput

0.232

Low

1230744

ZNT10
Calcium/manganese antiporter SLC30A10

1

0

High-throughput

0.232

Low

1230746

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.232

Low

1230764

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.232

Low

1230765

S39A9
Zinc transporter ZIP9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025