HitPredict

Interactor 1: K2C1 (P04264)
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
Gene: KRT1

Interactor 2: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	19738201, 22623428
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 739
+	Hs
		409001 K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		359464 K2C6A_HUMAN (2-512): 2.12e-75: 253: 62.43		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		409180 K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44		TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24
+	Hs
		234500 KRT83_HUMAN (79-563): 3.51e-87: 282: 44.47		DSCAM_HUMAN (10-207): 2.99e-15: 82.3: 12.87