HitPredict

Interactor 1: S100B (P04271)
Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B)
Gene: S100B

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	11264299, 2833519, 35063084
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007611 - learning or memory and 2 others more... GO:0007613 - memory GO:0043025 - neuronal cell body
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 92 Hs			1 758
+	Hs
		497264 HORN_HUMAN (1-92): 1.99e-34: 125: 30.44		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497147 FILA2_HUMAN (1-92): 4.58e-30: 112: 36.96		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496312 S10A1_HUMAN (2-89): 2.93e-33: 111: 60.23		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		416341 S10A9_HUMAN (1-91): 3.59e-29: 102: 36.96		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496690 S10AA_HUMAN (2-89): 2.16e-29: 102: 38.64		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496287 FILA_HUMAN (1-92): 7.85e-24: 95.3: 34.78		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		396671 S10A8_HUMAN (1-92): 4.18e-25: 91.4: 32.61		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		416558 S10A6_HUMAN (3-90): 7.15e-24: 87.9: 39.77		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497435 S10AG_HUMAN (2-92): 8.88e-23: 85.6: 28.26		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497487 S10AD_HUMAN (1-83): 3.55e-21: 81.4: 28.92		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		152595 S10A2_HUMAN (2-90): 1.34e-29: 102: 44.94		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Bt
		361268 S100B_BOVIN (1-92): 3.72e-32: 109: 96.74		TAU_BOVIN (1-291): 3.66e-12: 71.3: 40.00