HitPredict

Interactor 1: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Interactor 2: ICAM1 (P05362)
Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54)
Gene: ICAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 532
+	Hs
		399950 TBB5_HUMAN (1-429): 0: 714: 97.44		ICAM1_HUMAN (1-532): 7.16e-102: 318: 100.00
+	Hs
		400065 TBB3_HUMAN (1-444): 0: 714: 91.44		ICAM1_HUMAN (1-532): 7.16e-102: 318: 100.00
+	Hs
		400112 TBB6_HUMAN (1-433): 0: 708: 93.07		ICAM1_HUMAN (1-532): 7.16e-102: 318: 100.00
+	Hs
		400075 TBB8_HUMAN (1-427): 0: 702: 90.16		ICAM1_HUMAN (1-532): 7.16e-102: 318: 100.00
+	Hs
		427993 TBB5_HUMAN (1-429): 0: 714: 97.44		NCAM1_HUMAN (9-524): 1.88e-83: 278: 13.01
+	Rn
		530222 TBB2A_RAT (1-430): 0: 709: 96.28		NCAM1_RAT (9-524): 9.1e-85: 282: 13.64
+	Hs
		530247 TBB8_HUMAN (1-427): 0: 702: 90.16		ICAM2_HUMAN (13-227): 2.73e-70: 228: 33.04
+	Hs
		1037462 TBB3_HUMAN (1-444): 0: 714: 91.44		ROBO1_HUMAN (21-525): 1.61e-32: 135: 10.51
+	Hs
		381339 TBB4A_HUMAN (1-427): 0: 709: 100.00		ROBO1_HUMAN (21-525): 1.61e-32: 135: 10.51
+	Hs
		428008 TBB5_HUMAN (1-429): 0: 714: 97.44		VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57
+	Hs
		581663 TBB4B_HUMAN (1-427): 0: 713: 98.60		VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57
+	Hs
		581847 TBB6_HUMAN (1-433): 0: 708: 93.07		VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57
+	Hs
		581762 TBB8_HUMAN (1-427): 0: 702: 90.16		VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57