HitPredict

Interactor 1: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Interactor 2: PRTN3 (P24158)
Myeloblastin (EC 3.4.21.76) (AGP7) (C-ANCA antigen) (Leukocyte proteinase 3) (PR-3) (PR3) (Neutrophil proteinase 4) (NP-4) (P29) (Wegener autoantigen)
Gene: PRTN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 256
+	Hs
		428023 TBB5_HUMAN (1-429): 0: 714: 97.44		PRTN3_HUMAN (1-256): 5.43e-109: 316: 100.00
+	Hs
		428722 TBB3_HUMAN (1-444): 0: 714: 91.44		TRY2_HUMAN (27-251): 2.47e-99: 291: 33.90
+	Hs
		1037390 TBB3_HUMAN (1-444): 0: 714: 91.44		TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10
+	Hs
		428427 TBB5_HUMAN (1-429): 0: 714: 97.44		TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10
+	Hs
		933971 TBB4B_HUMAN (1-427): 0: 713: 98.60		TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10
+	Hs
		1046575 TBB2A_HUMAN (1-430): 0: 709: 96.28		TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10
+	Hs
		381298 TBB4A_HUMAN (1-427): 0: 709: 100.00		TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10
+	Hs
		1312808 TBB6_HUMAN (1-433): 0: 708: 93.07		TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10
+	Hs
		381216 TBB4A_HUMAN (1-427): 0: 709: 100.00		PRSS8_HUMAN (18-256): 1.49e-92: 277: 26.52
+	Hs
		1037334 TBB3_HUMAN (1-444): 0: 714: 91.44		KLK6_HUMAN (9-250): 1.54e-91: 271: 30.16
+	Hs
		1037427 TBB3_HUMAN (1-444): 0: 714: 91.44		KLK11_HUMAN (25-250): 6.76e-89: 266: 30.71
+	Hs
		427973 TBB5_HUMAN (1-429): 0: 714: 97.44		CATG_HUMAN (22-248): 1.63e-41: 144: 37.55
+	Hs
		428017 TBB5_HUMAN (1-429): 0: 714: 97.44		GRAH_HUMAN (22-250): 3.27e-41: 143: 37.08
+	Hs
		595528 TBB3_HUMAN (1-444): 0: 714: 91.44		GRAH_HUMAN (22-250): 3.27e-41: 143: 37.08
+	Hs
		381123 TBB4A_HUMAN (1-427): 0: 709: 100.00		GRAH_HUMAN (22-250): 3.27e-41: 143: 37.08
+	Hs
		439334 TBB8_HUMAN (1-427): 0: 702: 90.16		CATG_HUMAN (22-248): 1.63e-41: 144: 37.55
+	Hs
		595536 TBB8_HUMAN (1-427): 0: 702: 90.16		GRAH_HUMAN (22-250): 3.27e-41: 143: 37.08
+	Hs
		836354 TBB3_HUMAN (1-444): 0: 714: 91.44		GRAK_HUMAN (27-247): 7.67e-34: 124: 34.57
+	Mm
		371765 TBB4B_MOUSE (1-427): 0: 713: 98.60		CFAD_MOUSE (10-245): 1.33e-33: 124: 34.52
+	Hs
		420746 TBB8_HUMAN (1-427): 0: 702: 90.16		KLK1_HUMAN (15-247): 1.27e-31: 119: 33.96