Protein: RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha)

Gene: RPAB4, RPC10
Organism: Saccharomyces cerevisiae S288C
Interactions: 104
UniProt ID: P40422

Gene Ontology (top 5):
GO:0001172 - RNA-templated transcription
GO:0003677 - DNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594405

RPB3
DNA-directed RNA polymerase II subunit RPB3

15

4

Small-scale

0.981

High

402025

RPB1
DNA-directed RNA polymerase II subunit RPB1

5

9

Small-scale

0.902

High

644936

RPA2
DNA-directed RNA polymerase I subunit RPA135

4

6

Small-scale

0.891

High

534270

RPA1
DNA-directed RNA polymerase I subunit RPA190

4

9

Small-scale

0.881

High

647131

RPC2
DNA-directed RNA polymerase III subunit RPC2

3

6

Small-scale

0.827

High

459103

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

4

High-throughput

0.776

High

708746

TF3B
Transcription factor IIIB 70 kDa subunit

2

3

High-throughput

0.754

High

632171

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

5

1

Small-scale

0.697

High

632093

RPB4
DNA-directed RNA polymerase II subunit RPB4

4

1

Small-scale

0.676

High

632348

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

4

1

Small-scale

0.676

High

823712

RPA43
DNA-directed RNA polymerase I subunit RPA43

3

1

Small-scale

0.650

High

757330

RPB7
DNA-directed RNA polymerase II subunit RPB7

3

4

Small-scale

0.640

High

806930

RPB11
DNA-directed RNA polymerase II subunit RPB11

3

3

Small-scale

0.640

High

402220

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

9

High-throughput

0.618

High

470538

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

6

High-throughput

0.618

High

707280

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.618

High

518044

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.614

High

823714

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

3

0

Small-scale

0.613

High

823735

ASR1
Alcohol-sensitive RING finger protein 1

3

0

Small-scale

0.613

High

694561

SPT5
Transcription elongation factor SPT5

2

2

High-throughput

0.584

High

699958

RPB9
DNA-directed RNA polymerase II subunit RPB9

2

5

Small-scale

0.584

High

735010

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

1

High-throughput

0.584

High

748295

SPT4
Transcription elongation factor SPT4

2

1

High-throughput

0.584

High

818383

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

2

1

Small-scale

0.584

High

823709

T2FB
Transcription initiation factor IIF subunit beta

2

2

Small-scale

0.584

High

782349

RPF2
Ribosome biogenesis protein RPF2

2

0

High-throughput

0.576

High

823741

CMR1
DNA damage-binding protein CMR1

2

0

High-throughput

0.561

High

739658

SPT16
FACT complex subunit SPT16

2

0

Small-scale

0.559

High

763333

TAF14
Transcription initiation factor TFIID subunit 14

2

0

Small-scale

0.559

High

823706

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

823722

H3
Histone H3

2

0

Small-scale

0.559

High

823736

IWR1
RNA polymerase II nuclear localization protein IWR1

2

0

Small-scale

0.559

High

815457

RSP5
E3 ubiquitin-protein ligase RSP5

1

1

High-throughput

0.536

High

441372

KAPB
cAMP-dependent protein kinase type 2

1

0

High-throughput

0.513

High

823727

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.513

High

751899

TFC4
Transcription factor tau 131 kDa subunit

1

0

Small-scale

0.504

High

682920

MSH2
DNA mismatch repair protein MSH2

1

0

High-throughput

0.493

High

823180

RAD26
DNA repair and recombination protein RAD26

1

0

Small-scale

0.480

High

381126

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

381533

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

382141

H4
Histone H4

1

1

High-throughput

0.479

High

416129

SYTC
Threonine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

416246

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

561482

TBP
TATA-box-binding protein

1

1

High-throughput

0.479

High

581870

SYKC
Lysine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

632260

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

2

High-throughput

0.479

High

645061

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

1

High-throughput

0.479

High

700009

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

3

High-throughput

0.479

High

739531

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

5

High-throughput

0.479

High

748134

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

1

High-throughput

0.479

High

776300

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

4

High-throughput

0.479

High

781676

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

1

High-throughput

0.479

High

802556

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

802635

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.479

High

823713

TFC5
Transcription factor TFIIIB component B''

1

1

High-throughput

0.479

High

823718

GPN1
GPN-loop GTPase 1

1

5

High-throughput

0.479

High

823725

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

823726

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

823729

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

5

High-throughput

0.479

High

823739

GPN2
GPN-loop GTPase 2

1

5

Small-scale

0.479

High

395248

GCN4
General control transcription factor GCN4

1

0

Small-scale

0.460

High

408418

GAL4
Regulatory protein GAL4

1

0

Small-scale

0.460

High

624919

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

Small-scale

0.460

High

781093

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

0

Small-scale

0.460

High

806291

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

448314

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

460345

SYV
Valine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

576974

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.458

High

579515

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

609191

RPC7
DNA-directed RNA polymerase III subunit RPC7

1

0

High-throughput

0.458

High

674414

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.458

High

736011

SP110
Spindle pole body component 110

1

0

High-throughput

0.458

High

737882

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.458

High

739386

ZUO1
Zuotin

1

0

High-throughput

0.458

High

740803

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

Small-scale

0.458

High

745766

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

780374

ELF1
Transcription elongation factor 1

1

0

High-throughput

0.458

High

804206

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.458

High

815087

SS120
Protein SSP120

1

0

High-throughput

0.458

High

823708

T2FA
Transcription initiation factor IIF subunit alpha

1

0

High-throughput

0.458

High

823711

BUD27
Bud site selection protein 27

1

0

High-throughput

0.458

High

823715

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

823716

NET1
Nucleolar protein NET1

1

0

High-throughput

0.458

High

823717

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.458

High

823719

RPA14
DNA-directed RNA polymerase I subunit RPA14

1

0

High-throughput

0.458

High

823720

PDR16
Phosphatidylinositol transfer protein PDR16

1

0

High-throughput

0.458

High

823721

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

823723

SEN1
Helicase SEN1

1

0

High-throughput

0.458

High

823724

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.458

High

823730

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

823731

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

823732

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

823734

CDC73
Cell division control protein 73

1

0

High-throughput

0.458

High

823738

SGO1
Shugoshin

1

0

High-throughput

0.458

High

823740

YB11B
Transposon Ty1-BL Gag-Pol polyprotein

1

0

High-throughput

0.458

High

823733

GPN3
GPN-loop GTPase 3

1

5

Small-scale

0.437

High

740414

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.426

High

823707

INA22
Inner membrane assembly complex subunit 22

1

0

High-throughput

0.269

Low

148878

CET1
mRNA-capping enzyme subunit beta

1

0

High-throughput

0.249

Low

808745

ATU2
Copper-transporting ATPase

1

0

High-throughput

0.249

Low

812365

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

823710

EMP47
Protein EMP47

1

0

High-throughput

0.249

Low

823728

PDR15
ATP-dependent permease PDR15

1

0

High-throughput

0.249

Low

823737

ENB1
Siderophore iron transporter ENB1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025