HitPredict

Interactor 1: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 530
+	Hs
		1037333 TBB3_HUMAN (1-444): 0: 714: 91.44		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1046531 TBB2A_HUMAN (1-430): 0: 709: 96.28		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368829 TBB5_HUMAN (1-429): 0: 714: 97.44		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369548 TBB3_HUMAN (1-444): 0: 714: 91.44		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370338 TBB6_HUMAN (1-433): 0: 708: 93.07		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369732 TBB8_HUMAN (1-427): 0: 702: 90.16		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		320154 TBB5_HUMAN (1-429): 0: 714: 97.44		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		377012 TBB5_HUMAN (1-429): 0: 714: 97.44		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377239 TBB4B_HUMAN (1-427): 0: 713: 98.60		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Rn
		415143 TBB2B_RAT (1-430): 0: 712: 96.74		GCR_RAT (3-495): 5.89e-100: 321: 23.03
+	Hs
		381124 TBB4A_HUMAN (1-427): 0: 709: 100.00		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		414415 TBB5_HUMAN (1-429): 0: 714: 97.44		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		414483 TBB4B_HUMAN (1-427): 0: 713: 98.60		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82