Interactor 1: EGFR (P04412)
Epidermal growth factor receptor (Egfr) (EC 2.7.10.1) (Drosophila relative of ERBB) (Gurken receptor) (Protein torpedo)
Gene: EGFR

Interactor 2: VAV (Q9NHV9)
Protein vav (DroVav) (dVAV)
Gene: VAV

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.874

The method score is based on:

Property Details
Experiments 22028469, 17637670, 23525006, 17629483
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~PK_Tyr_Ser-Thr, CH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1
Common GO terms GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0007298 - border follicle cell migration
GO:0007391 - dorsal closure
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1426
Dm

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Last updated: 15 Jul 2024