Interactor 1: EGFR (P04412)
Epidermal growth factor receptor (Egfr) (EC 2.7.10.1) (Drosophila relative of ERBB) (Gurken receptor) (Protein torpedo)
Gene: EGFR

Interactor 2: Q9V3C8 (Q9V3C8)
DShc protein (FI07258p) (SHC-adaptor protein)
Gene: Shc

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.854

The method score is based on:

Property Details
Experiments 17637670, 8577769, 7651398
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2
Common GO terms GO:0001751 - compound eye photoreceptor cell differentiation
GO:0005886 - plasma membrane
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0007298 - border follicle cell migration
GO:0007426 - tracheal outgrowth, open tracheal system
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024