Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2
Interactor 2: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.95 | 1.00 | 0.978 |
The method score is based on:
Property | Details |
---|---|
Experiments | 14576349, 8665853, 25315821, 8816440, 11526509, 30898150, 25898135, 19060928, 19077306, 16843263, 17148612, 21203579, 22733765, 21255571 |
Identification Methods | affinity chromatography technology, enzymatic study, two hybrid, pull down, unspecified method, protein complementation assay, protein kinase assay, beta galactosidase complementation, fluorescent resonance energy transfer, anti tag coimmunoprecipitation and 1 others
more... |
Interaction Type | physical association, direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Furin-like~Furin-like, Furin-like~GF_recep_IV, Furin-like~Recep_L_domain, GF_recep_IV~GF_recep_IV, GF_recep_IV~Recep_L_domain, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, Recep_L_domain~Recep_L_domain |
Common GO terms | GO:0001042 - RNA polymerase I core binding GO:0001934 - positive regulation of protein phosphorylation GO:0002116 - semaphorin receptor complex GO:0004713 - protein tyrosine kinase activity GO:0004714 - transmembrane receptor protein tyrosine kinase activity and 64 others more... |
Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores
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Last updated: 15 Jul 2024