HitPredict

Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Interactor 2: TXTP (P53007)
Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Mitochondrial citrate carrier) (CIC) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)
Gene: SLC25A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	24189400
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 311
+	Hs
		383524 ERBB2_HUMAN (1-1255): 0: 1282: 100.00		ADT2_HUMAN (116-310): 3.42e-36: 133: 23.67
+	Hs
		383979 ERBB2_HUMAN (1-1255): 0: 1282: 100.00		GHC1_HUMAN (21-297): 1.35e-25: 105: 27.42
+	Hs
		337757 EGFR_HUMAN (16-1253): 0: 1070: 48.40		ADT2_HUMAN (116-310): 3.42e-36: 133: 23.67
+	Hs
		339108 EGFR_HUMAN (16-1253): 0: 1070: 48.40		S2513_HUMAN (1-117): 7.19e-25: 106: 26.89
+	Hs
		397269 ERBB3_HUMAN (5-1254): 0: 1041: 38.55		ADT2_HUMAN (116-310): 3.42e-36: 133: 23.67
+	Hs
		518250 ERBB3_HUMAN (5-1254): 0: 1041: 38.55		ADT3_HUMAN (121-310): 2.98e-35: 131: 22.28
+	Hs
		411496 INSR_HUMAN (584-1066): 2.91e-107: 371: 23.19		GHC1_HUMAN (21-297): 1.35e-25: 105: 27.42
+	Hs
		397233 IGF1R_HUMAN (337-633): 4.59e-20: 99.1: 22.92		ADT2_HUMAN (116-310): 3.42e-36: 133: 23.67
+	Rn
		544923 INSR_RAT (357-634): 2.53e-16: 87.2: 19.87		Q9EP88_RAT (221-311): 7e-18: 84.5: 27.27