HitPredict

Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Interactor 2: AP1M2 (Q9Y6Q5)
AP-1 complex subunit mu-2 (AP-mu chain family member mu1B) (Adaptor protein complex AP-1 subunit mu-2) (Adaptor-related protein complex 1 subunit mu-2) (Clathrin assembly protein complex 1 mu-2 medium chain 2) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Mu-adaptin 2) (Mu1B-adaptin)
Gene: AP1M2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34591642
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 423
+	Hs
		338940 EGFR_HUMAN (16-1253): 0: 1070: 48.40		AP1M1_HUMAN (1-422): 0: 555: 79.86
+	Hs
		339212 EGFR_HUMAN (16-1253): 0: 1070: 48.40		AP1M2_HUMAN (1-423): 0: 540: 100.00
+	Hs
		602043 ERBB3_HUMAN (5-1254): 0: 1041: 38.55		AP1M2_HUMAN (1-423): 0: 540: 100.00
+	Hs
		338822 EGFR_HUMAN (16-1253): 0: 1070: 48.40		AP2M1_HUMAN (5-421): 3.67e-167: 478: 37.88
+	Hs
		339173 EGFR_HUMAN (16-1253): 0: 1070: 48.40		AP3M1_HUMAN (5-422): 1.56e-137: 401: 29.17
+	Hs
		665310 EPHA2_HUMAN (671-1023): 4.87e-117: 390: 33.06		AP2M1_HUMAN (5-421): 3.67e-167: 478: 37.88
+	Rn
		544829 INSR_RAT (357-634): 2.53e-16: 87.2: 19.87		AP1M1_RAT (1-422): 0: 555: 79.86
+	Hs
		983696 FAK1_HUMAN (706-984): 1.9e-53: 206: 39.07		AP3M1_HUMAN (5-422): 1.56e-137: 401: 29.17
+	Rn
		544815 INSR_RAT (357-634): 2.53e-16: 87.2: 19.87		AP2M1_RAT (5-421): 3.67e-167: 478: 37.88