Protein: RM02
Large ribosomal subunit protein uL2m (39S ribosomal protein L2, mitochondrial) (L2mt) (MRP-L2)

Gene: RM02, MRPL2
Organism: Homo sapiens
Interactions: 220
UniProt ID: Q5T653

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1213350

RT30
Large ribosomal subunit protein mL65

4

0

High-throughput

0.846

High

1213308

MTEF3
Transcription termination factor 3, mitochondrial

3

0

High-throughput

0.796

High

1213334

RM37
Large ribosomal subunit protein mL37

3

0

High-throughput

0.796

High

1094027

RM28
Large ribosomal subunit protein bL28m

4

1

High-throughput

0.691

High

1123312

ICT1
Large ribosomal subunit protein mL62

4

1

High-throughput

0.691

High

1213349

RM47
Large ribosomal subunit protein uL29m

4

1

High-throughput

0.691

High

1213286

RM50
Large ribosomal subunit protein mL50

4

0

High-throughput

0.667

High

969259

RS8
Small ribosomal subunit protein eS8

3

3

High-throughput

0.667

High

1213331

RM04
Large ribosomal subunit protein uL4m

3

3

High-throughput

0.667

High

350893

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

3

3

High-throughput

0.650

High

1213361

RM39
Large ribosomal subunit protein mL39

3

0

High-throughput

0.638

High

1213277

RM10
Large ribosomal subunit protein uL10m

3

0

High-throughput

0.634

High

1213330

RM09
Large ribosomal subunit protein bL9m

3

0

High-throughput

0.634

High

1213363

RM35
Large ribosomal subunit protein bL35m

3

0

High-throughput

0.634

High

1213384

RM42
Large ribosomal subunit protein mL42

3

0

High-throughput

0.634

High

1213332

RM01
Large ribosomal subunit protein uL1m

2

1

High-throughput

0.628

High

1213351

NGRN
Neugrin

3

0

High-throughput

0.622

High

1194142

LARP7
La-related protein 7

2

5

High-throughput

0.611

High

1213356

DDX28
Probable ATP-dependent RNA helicase DDX28

2

5

High-throughput

0.611

High

1213379

RM11
Large ribosomal subunit protein uL11m

2

2

High-throughput

0.611

High

61949

GTPBA
GTP-binding protein 10

2

4

High-throughput

0.601

High

914631

RM12
Large ribosomal subunit protein bL12m

2

1

High-throughput

0.601

High

994589

YBOX1
Y-box-binding protein 1

2

12

Small-scale

0.601

High

1213275

RM21
Large ribosomal subunit protein bL21m

2

1

High-throughput

0.601

High

1213329

RM13
Large ribosomal subunit protein uL13m

2

6

High-throughput

0.601

High

1213344

RM44
Large ribosomal subunit protein mL44

2

1

High-throughput

0.601

High

1213360

RM16
Large ribosomal subunit protein uL16m

2

2

High-throughput

0.601

High

1213365

RM27
Large ribosomal subunit protein bL27m

2

2

High-throughput

0.601

High

1213376

YBOX2
Y-box-binding protein 2

2

12

High-throughput

0.601

High

271058

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

2

0

High-throughput

0.576

High

1158222

RM23
Large ribosomal subunit protein uL23m

2

0

High-throughput

0.576

High

1196111

RM51
Large ribosomal subunit protein mL51

2

0

High-throughput

0.576

High

1213276

RM55
Large ribosomal subunit protein mL55

2

0

High-throughput

0.576

High

1213278

RM52
Large ribosomal subunit protein mL52

2

0

High-throughput

0.576

High

1213281

RM41
Large ribosomal subunit protein mL41

2

0

High-throughput

0.576

High

1213289

G45IP
Large ribosomal subunit protein mL64

2

0

High-throughput

0.576

High

1213291

RM30
Large ribosomal subunit protein uL30m

2

0

High-throughput

0.576

High

1213309

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

2

0

High-throughput

0.576

High

1213311

RM53
Large ribosomal subunit protein mL53

2

0

High-throughput

0.576

High

1213314

RM48
Large ribosomal subunit protein mL48

2

0

High-throughput

0.576

High

1213316

RCC1L
RCC1-like G exchanging factor-like protein

2

0

High-throughput

0.576

High

1213319

RM34
Large ribosomal subunit protein bL34m

2

0

High-throughput

0.576

High

1213328

RM20
Large ribosomal subunit protein bL20m

2

0

High-throughput

0.576

High

1213337

RM18
Large ribosomal subunit protein uL18m

2

0

High-throughput

0.576

High

1213358

RT18A
Large ribosomal subunit protein mL66

2

0

High-throughput

0.576

High

1213359

RM22
Large ribosomal subunit protein uL22m

2

0

High-throughput

0.576

High

835689

KPCI
Protein kinase C iota type

2

1

High-throughput

0.571

High

1209219

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

1

High-throughput

0.571

High

1213366

MRES1
Mitochondrial transcription rescue factor 1

2

0

High-throughput

0.559

High

631271

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.547

High

132485

CDC7
Cell division cycle 7-related protein kinase

1

2

High-throughput

0.536

High

257880

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

2

High-throughput

0.536

High

338136

NSA2
Ribosome biogenesis protein NSA2 homolog

1

3

High-throughput

0.536

High

477804

RM03
Large ribosomal subunit protein uL3m

1

5

High-throughput

0.536

High

599799

YBOX3
Y-box-binding protein 3

1

12

High-throughput

0.536

High

615822

RL17
Large ribosomal subunit protein uL22

1

3

High-throughput

0.536

High

824183

RL13A
Large ribosomal subunit protein uL13

1

6

High-throughput

0.536

High

842402

RL35
Large ribosomal subunit protein uL29

1

2

High-throughput

0.536

High

853699

MK08
Mitogen-activated protein kinase 8

1

1

High-throughput

0.536

High

858950

RL27A
Large ribosomal subunit protein uL15

1

1

High-throughput

0.536

High

860232

RS9
Small ribosomal subunit protein uS4

1

3

High-throughput

0.536

High

860782

RS10
Small ribosomal subunit protein eS10

1

2

High-throughput

0.536

High

959819

RS3A
Small ribosomal subunit protein eS1

1

3

High-throughput

0.536

High

964120

RL37
Large ribosomal subunit protein eL37

1

2

High-throughput

0.536

High

978561

RL23A
Large ribosomal subunit protein uL23

1

3

High-throughput

0.536

High

982461

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.536

High

1011462

RT10
Small ribosomal subunit protein uS10m

1

2

High-throughput

0.536

High

1011810

RT05
Small ribosomal subunit protein uS5m

1

3

High-throughput

0.536

High

1012195

RT11
Small ribosomal subunit protein uS11m

1

4

High-throughput

0.536

High

1012856

RT09
Small ribosomal subunit protein uS9m

1

2

High-throughput

0.536

High

1016045

RL19
Large ribosomal subunit protein eL19

1

2

High-throughput

0.536

High

1016471

SRSF3
Serine/arginine-rich splicing factor 3

1

7

High-throughput

0.536

High

1027513

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

High-throughput

0.536

High

1112045

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.536

High

1115713

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

2

High-throughput

0.536

High

1148696

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

2

High-throughput

0.536

High

1155449

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.536

High

1213266

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

3

High-throughput

0.536

High

1213268

RM14
Large ribosomal subunit protein uL14m

1

1

High-throughput

0.536

High

1213269

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

1

High-throughput

0.536

High

1213274

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

1

High-throughput

0.536

High

1213279

RBM45
RNA-binding protein 45

1

2

High-throughput

0.536

High

1213282

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

2

High-throughput

0.536

High

1213287

RM43
Large ribosomal subunit protein mL43

1

1

High-throughput

0.536

High

1213290

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

1

2

High-throughput

0.536

High

1213292

RS4Y2
Small ribosomal subunit protein eS4, Y isoform 2

1

1

High-throughput

0.536

High

1213293

DDX54
ATP-dependent RNA helicase DDX54

1

13

High-throughput

0.536

High

1213294

TFB1M
Dimethyladenosine transferase 1, mitochondrial

1

1

High-throughput

0.536

High

1213295

SRS12
Serine/arginine-rich splicing factor 12

1

7

High-throughput

0.536

High

1213306

RM38
Large ribosomal subunit protein mL38

1

1

High-throughput

0.536

High

1213315

GWL
Serine/threonine-protein kinase greatwall

1

2

High-throughput

0.536

High

1213339

RM46
Large ribosomal subunit protein mL46

1

1

High-throughput

0.536

High

1213345

LN28A
Protein lin-28 homolog A

1

13

High-throughput

0.536

High

1213348

MOV10
Helicase MOV-10

1

1

High-throughput

0.536

High

1213354

DDX21
Nucleolar RNA helicase 2

1

7

High-throughput

0.536

High

1213355

RM17
Large ribosomal subunit protein bL17m

1

2

High-throughput

0.536

High

1213362

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

1

High-throughput

0.536

High

1213364

RM15
Large ribosomal subunit protein uL15m

1

3

High-throughput

0.536

High

1213375

RT07
Small ribosomal subunit protein uS7m

1

1

High-throughput

0.536

High

1213378

RT02
Small ribosomal subunit protein uS2m

1

2

High-throughput

0.536

High

1213380

RT16
Small ribosomal subunit protein bS16m

1

1

High-throughput

0.536

High

1213381

RT18C
Small ribosomal subunit protein bS18m

1

1

High-throughput

0.536

High

1213382

RBM19
Probable RNA-binding protein 19

1

1

High-throughput

0.536

High

75971

B4DEF8
Large ribosomal subunit protein mL45

1

0

High-throughput

0.513

High

156461

ACPM
Acyl carrier protein, mitochondrial

1

0

High-throughput

0.513

High

214301

MSI1H
RNA-binding protein Musashi homolog 1

1

0

High-throughput

0.513

High

280038

RM33
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.513

High

360273

COX1
Cytochrome c oxidase subunit 1

1

0

High-throughput

0.513

High

397742

NU5M
NADH-ubiquinone oxidoreductase chain 5

1

0

High-throughput

0.513

High

471072

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

788059

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

841017

FRK
Tyrosine-protein kinase FRK

1

0

High-throughput

0.513

High

882321

RM19
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.513

High

902491

RT29
Small ribosomal subunit protein mS29

1

0

High-throughput

0.513

High

1011097

RT22
Small ribosomal subunit protein mS22

1

0

High-throughput

0.513

High

1011283

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.513

High

1011627

RT35
Small ribosomal subunit protein mS35

1

0

High-throughput

0.513

High

1012415

RT21
Small ribosomal subunit protein bS21m

1

0

High-throughput

0.513

High

1012520

RT34
Small ribosomal subunit protein mS34

1

0

High-throughput

0.513

High

1103982

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.513

High

1141495

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.513

High

1203555

ZN326
DBIRD complex subunit ZNF326

1

0

High-throughput

0.513

High

1213267

RM54
Large ribosomal subunit protein mL54

1

0

High-throughput

0.513

High

1213283

SUV3
ATP-dependent RNA helicase SUPV3L1, mitochondrial

1

0

High-throughput

0.513

High

1213296

RT27
Small ribosomal subunit protein mS27

1

0

High-throughput

0.513

High

1213297

RT31
Small ribosomal subunit protein mS31

1

0

High-throughput

0.513

High

1213303

RM24
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.513

High

1213310

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.513

High

1213313

PTCD3
Small ribosomal subunit protein mS39

1

0

High-throughput

0.513

High

1213320

RT63
Large ribosomal subunit protein mL63

1

0

High-throughput

0.513

High

1213327

RM32
Large ribosomal subunit protein bL32m

1

0

High-throughput

0.513

High

1213333

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.513

High

1213347

MRM3
rRNA methyltransferase 3, mitochondrial

1

0

High-throughput

0.513

High

1213352

RM40
Large ribosomal subunit protein mL40

1

0

High-throughput

0.513

High

1213372

RT33
Small ribosomal subunit protein mS33

1

0

High-throughput

0.513

High

1213374

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.513

High

1213377

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1213270

RBMS3
RNA-binding motif, single-stranded-interacting protein 3

1

2

High-throughput

0.489

High

1213370

NEB1
Neurabin-1

1

3

High-throughput

0.489

High

889585

CLK2
Dual specificity protein kinase CLK2

1

3

High-throughput

0.481

High

1213304

EXOS8
Exosome complex component RRP43

1

1

High-throughput

0.481

High

1213383

KLF12
Krueppel-like factor 12

1

0

High-throughput

0.479

High

61521

VWA8
von Willebrand factor A domain-containing protein 8

1

1

High-throughput

0.479

High

183661

RT12
Small ribosomal subunit protein uS12m

1

2

High-throughput

0.479

High

241929

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

281974

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.479

High

287307

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

315674

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

372244

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

406267

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

472804

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

2

High-throughput

0.479

High

693785

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.479

High

872413

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

882714

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

960139

RL26
Large ribosomal subunit protein uL24

1

5

High-throughput

0.479

High

1058066

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1083635

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.479

High

1087414

GRSF1
G-rich sequence factor 1

1

4

Small-scale

0.479

High

1092148

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

1113325

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1117754

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

1213265

MRM1
rRNA methyltransferase 1, mitochondrial

1

4

High-throughput

0.479

High

1213273

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.479

High

1213298

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1213299

KAT6A
Histone acetyltransferase KAT6A

1

3

High-throughput

0.479

High

1213300

H2B1H
Histone H2B type 1-H

1

1

High-throughput

0.479

High

1213302

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

1213305

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

3

High-throughput

0.479

High

1213317

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

1213318

H2B1L
Histone H2B type 1-L

1

1

High-throughput

0.479

High

1213323

MTG1
Mitochondrial ribosome-associated GTPase 1

1

6

High-throughput

0.479

High

1213340

MTRFR
Mitochondrial translation release factor in rescue

1

3

High-throughput

0.479

High

1213341

MTG2
Mitochondrial ribosome-associated GTPase 2

1

6

High-throughput

0.479

High

1213342

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.479

High

1213353

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1213367

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

3

High-throughput

0.479

High

1213368

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1213371

RL26L
Ribosomal protein uL24-like

1

5

High-throughput

0.479

High

66215

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

279788

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

828802

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

841776

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

851913

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

1213280

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

1213307

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1213321

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1213322

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

1213324

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1213325

TR61B
tRNA

1

0

High-throughput

0.458

High

1213326

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1213336

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

1213338

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1213343

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1213346

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

3

High-throughput

0.457

High

430017

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

1213357

ATD3A
ATPase family AAA domain-containing protein 3A

1

2

High-throughput

0.445

High

317855

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.437

High

970634

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1140395

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

1213264

Q6ICH2
single-stranded DNA cytosine deaminase

1

1

High-throughput

0.437

High

1213271

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

653368

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

1213301

TRI63
E3 ubiquitin-protein ligase TRIM63

1

4

High-throughput

0.417

High

73410

B2CML4
single-stranded DNA cytosine deaminase

1

1

High-throughput

0.407

High

1213263

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.407

High

635725

RASA1
Ras GTPase-activating protein 1

2

0

High-throughput

0.298

High

1213288

DOCK8
Dedicator of cytokinesis protein 8

2

0

High-throughput

0.298

High

1213284

CKLF4
CKLF-like MARVEL transmembrane domain-containing protein 4

1

0

High-throughput

0.282

High

214439

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

0

High-throughput

0.279

Low

391279

FRIL
Ferritin light chain

1

0

High-throughput

0.279

Low

1178763

AAK1
AP2-associated protein kinase 1

1

0

High-throughput

0.279

Low

1210454

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.279

Low

1213272

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.279

Low

1213369

KLHL3
Kelch-like protein 3

1

0

High-throughput

0.279

Low

1213373

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

1015506

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

1213285

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1213335

DYH6
Dynein axonemal heavy chain 6

1

0

High-throughput

0.249

Low

58833

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low

1213312

NTCP4
Sodium/bile acid cotransporter 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025