HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030425 - dendrite GO:0043025 - neuronal cell body
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 589
+	Hs
		507873 FGFR1_HUMAN (195-794): 0: 545: 26.34		2AAB_HUMAN (9-589): 7.23e-158: 466: 86.40
+	Hs
		268573 NTRK1_HUMAN (1-796): 0: 621: 100.00		SF3B1_HUMAN (12-589): 2.5e-28: 122: 13.20
+	Hs
		385270 NTRK1_HUMAN (1-796): 0: 621: 100.00		GCN1_HUMAN (28-589): 5.37e-25: 112: 16.01
+	Hs
		385296 NTRK1_HUMAN (1-796): 0: 621: 100.00		TNPO1_HUMAN (24-483): 2.91e-20: 97.2: 15.05
+	Hs
		385222 NTRK1_HUMAN (1-796): 0: 621: 100.00		PP4R1_HUMAN (325-583): 8.14e-09: 60.9: 17.78
+	Hs
		435712 IGF1R_HUMAN (493-777): 6.97e-71: 255: 42.61		GCN1_HUMAN (28-589): 5.37e-25: 112: 16.01
+	Hs
		435716 IGF1R_HUMAN (493-777): 6.97e-71: 255: 42.61		TNPO1_HUMAN (24-483): 2.91e-20: 97.2: 15.05