HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032991 - protein-containing complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 835
+	Hs
		384333 NTRK1_HUMAN (1-796): 0: 621: 100.00		PML_HUMAN (29-609): 1.21e-57: 214: 14.00
+	Hs
		385726 NTRK1_HUMAN (1-796): 0: 621: 100.00		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		170207 NTRK1_HUMAN (1-796): 0: 621: 100.00		TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55
+	Hs
		385082 NTRK1_HUMAN (1-796): 0: 621: 100.00		TRI46_HUMAN (53-402): 1.23e-33: 140: 14.74
+	Hs
		609193 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		TRI23_HUMAN (38-421): 2.37e-56: 205: 14.42
+	Hs
		584931 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		RO52_HUMAN (104-502): 1.58e-48: 180: 12.94
+	Hs
		968473 ROR2_HUMAN (515-783): 2.79e-66: 239: 43.91		TRIM9_HUMAN (93-529): 4.48e-51: 193: 13.30