HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 504
+	Hs
		385480 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBL1R_HUMAN (134-466): 1.2e-76: 251: 14.57
+	Hs
		384438 NTRK1_HUMAN (1-796): 0: 621: 100.00		LIS1_HUMAN (302-504): 3.93e-56: 194: 19.11
+	Hs
		196939 NTRK1_HUMAN (1-796): 0: 621: 100.00		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84
+	Hs
		384596 NTRK1_HUMAN (1-796): 0: 621: 100.00		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		609202 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		LIS1_HUMAN (302-504): 3.93e-56: 194: 19.11
+	Hs
		994668 DDR1_HUMAN (507-778): 1.77e-67: 242: 45.49		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		1313658 ALK_HUMAN (505-790): 8.72e-63: 231: 42.07		KTNB1_HUMAN (282-504): 4.25e-12: 70.5: 27.07