HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0048666 - neuron development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 796 Hs			1 761
+	Hs
		385705 NTRK1_HUMAN (1-796): 0: 621: 100.00		ASAP1_HUMAN (2-606): 1.67e-61: 226: 17.06
+	Hs
		385363 NTRK1_HUMAN (1-796): 0: 621: 100.00		AGAP3_HUMAN (2-223): 6.5e-55: 205: 34.22
+	Hs
		195775 NTRK1_HUMAN (1-796): 0: 621: 100.00		ASAP2_HUMAN (2-506): 1.34e-50: 193: 15.20
+	Hs
		385364 NTRK1_HUMAN (1-796): 0: 621: 100.00		ARAP1_HUMAN (8-205): 6.26e-49: 188: 29.35
+	Hs
		508262 FGFR1_HUMAN (195-794): 0: 545: 26.34		ASAP1_HUMAN (2-606): 1.67e-61: 226: 17.06
+	Hs
		385170 NTRK1_HUMAN (1-796): 0: 621: 100.00		ANR44_HUMAN (170-522): 5.73e-36: 148: 12.05
+	Hs
		384666 NTRK1_HUMAN (1-796): 0: 621: 100.00		ANK2_HUMAN (162-494): 7.25e-30: 129: 9.52
+	Hs
		608185 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		ASAP1_HUMAN (2-606): 1.67e-61: 226: 17.06
+	Hs
		166874 NTRK1_HUMAN (1-796): 0: 621: 100.00		ANR28_HUMAN (52-250): 1.89e-18: 92.5: 11.06
+	Hs
		507971 FGFR1_HUMAN (195-794): 0: 545: 26.34		ANK3_HUMAN (93-695): 4.85e-40: 162: 12.34
+	Hs
		474791 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		POTEI_HUMAN (31-683): 3.04e-60: 222: 12.85
+	Hs
		1021409 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		ANK3_HUMAN (93-695): 4.85e-40: 162: 12.34
+	Hs
		507954 FGFR1_HUMAN (195-794): 0: 545: 26.34		ANK2_HUMAN (162-494): 7.25e-30: 129: 9.52
+	Hs
		609490 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		ARAP1_HUMAN (8-205): 6.26e-49: 188: 29.35
+	Hs
		507831 FGFR1_HUMAN (195-794): 0: 545: 26.34		ANK1_HUMAN (163-647): 1.66e-27: 122: 10.92
+	Hs
		434183 RET_HUMAN (391-794): 3.5e-114: 374: 30.44		ANK3_HUMAN (93-695): 4.85e-40: 162: 12.34
+	Hs
		1088156 DDR2_HUMAN (499-781): 3.37e-72: 254: 44.55		ASAP1_HUMAN (2-606): 1.67e-61: 226: 17.06
+	Hs
		411283 INSR_HUMAN (493-777): 3e-68: 248: 42.62		POTEJ_HUMAN (47-683): 1.81e-59: 220: 12.31
+	Hs
		411483 INSR_HUMAN (493-777): 3e-68: 248: 42.62		AGAP2_HUMAN (2-223): 3.67e-52: 198: 32.00
+	Mm
		546273 INSR_MOUSE (493-777): 3.11e-66: 241: 41.95		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28