Protein: LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C]

Gene: LMNA
Organism: Mus musculus
Interactions: 81
UniProt ID: P48678

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005638 - lamin filament
GO:0005652 - nuclear lamina
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

876539

SUN2
SUN domain-containing protein 2

3

7

Small-scale

0.633

High

575058

LMNB1
Lamin-B1

1

19

Small-scale

0.618

High

639437

LMNB2
Lamin-B2

1

19

Small-scale

0.618

High

876559

SUN1
SUN domain-containing protein 1

2

9

Small-scale

0.584

High

876533

Q6IFZ8
Predicted gene 5414

1

20

Small-scale

0.553

High

876527

MLIP
Muscular LMNA-interacting protein

1

4

Small-scale

0.523

High

59586

A2AM57
Inversin

1

9

High-throughput

0.489

High

876562

NPHP1
Nephrocystin-1

1

3

High-throughput

0.489

High

59113

TM201
Transmembrane protein 201

1

3

Small-scale

0.479

High

147623

EMD
Emerin

1

4

Small-scale

0.479

High

147730

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

5

High-throughput

0.479

High

237400

PSB5
Proteasome subunit beta type-5

1

1

Small-scale

0.479

High

267033

1433S
14-3-3 protein sigma

1

20

Small-scale

0.479

High

465808

ENPL
Endoplasmin

1

2

Small-scale

0.479

High

659098

XRCC6
X-ray repair cross-complementing protein 6

1

2

Small-scale

0.479

High

728512

AKT1
RAC-alpha serine/threonine-protein kinase

1

14

Small-scale

0.479

High

846981

H14
Histone H1.4

1

5

Small-scale

0.479

High

876516

ATX1
Ataxin-1

1

5

High-throughput

0.479

High

876517

RAB10
Ras-related protein Rab-10

1

4

Small-scale

0.479

High

876518

RAB6B
Ras-related protein Rab-6B

1

11

Small-scale

0.479

High

876519

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

20

Small-scale

0.479

High

876520

ACTG
Actin, cytoplasmic 2

1

3

Small-scale

0.479

High

876521

UBC9
SUMO-conjugating enzyme UBC9

1

8

Small-scale

0.479

High

876522

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

5

Small-scale

0.479

High

876523

TOP2A
DNA topoisomerase 2-alpha

1

5

Small-scale

0.479

High

876525

STING
Stimulator of interferon genes protein

1

3

High-throughput

0.479

High

876526

LBR
Delta(14)-sterol reductase LBR

1

5

Small-scale

0.479

High

876528

CBX5
Chromobox protein homolog 5

1

7

Small-scale

0.479

High

876529

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

9

Small-scale

0.479

High

876530

TIF1B
Transcription intermediary factor 1-beta

1

20

Small-scale

0.479

High

876534

SYNE2
Nesprin-2

1

13

Small-scale

0.479

High

876535

SPOP
Speckle-type POZ protein

1

10

High-throughput

0.479

High

876536

FACD2
Fanconi anemia group D2 protein homolog

1

12

High-throughput

0.479

High

876537

TNPO1
Transportin-1

1

4

Small-scale

0.479

High

876546

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

8

Small-scale

0.479

High

876548

EED
Polycomb protein EED

1

15

High-throughput

0.479

High

876549

TOIP1
Torsin-1A-interacting protein 1

1

3

Small-scale

0.479

High

876551

RBM10
RNA-binding protein 10

1

3

Small-scale

0.479

High

876552

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

1

Small-scale

0.479

High

876553

RAB5A
Ras-related protein Rab-5A

1

9

Small-scale

0.479

High

876554

NRX1A
Neurexin-1

1

3

High-throughput

0.479

High

876555

SERB1
SERPINE1 mRNA-binding protein 1

1

4

Small-scale

0.479

High

876556

LUC7L
Putative RNA-binding protein Luc7-like 1

1

1

Small-scale

0.479

High

876557

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

4

Small-scale

0.479

High

876566

MAN1
Inner nuclear membrane protein Man1

1

14

Small-scale

0.479

High

876567

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

11

Small-scale

0.479

High

876568

RED
Protein Red

1

3

Small-scale

0.479

High

876569

DX39B
Spliceosome RNA helicase Ddx39b

1

20

Small-scale

0.479

High

876570

STRAP
Serine-threonine kinase receptor-associated protein

1

10

Small-scale

0.479

High

876532

Q6GTZ3
Idb1 protein

1

0

Small-scale

0.458

High

876545

MYH9
Myosin-9

1

0

Small-scale

0.458

High

467749

SODC
Superoxide dismutase [Cu-Zn]

1

7

High-throughput

0.445

High

591015

KPCE
Protein kinase C epsilon type

1

10

Small-scale

0.445

High

876547

SATB2
DNA-binding protein SATB2

1

2

Small-scale

0.445

High

876558

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

7

High-throughput

0.445

High

147443

SC22B
Vesicle-trafficking protein SEC22b

1

7

Small-scale

0.437

High

205303

ANXA3
Annexin A3

1

5

Small-scale

0.437

High

398169

CFAD
Complement factor D

1

8

High-throughput

0.437

High

723289

SSR3
Somatostatin receptor type 3

1

4

High-throughput

0.437

High

770486

RAB5C
Ras-related protein Rab-5C

1

11

Small-scale

0.437

High

876512

RAB7A
Ras-related protein Rab-7a

1

8

Small-scale

0.437

High

876514

PIPNB
Phosphatidylinositol transfer protein beta isoform

1

1

Small-scale

0.437

High

876515

RAB2A
Ras-related protein Rab-2A

1

4

Small-scale

0.437

High

876524

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

13

High-throughput

0.437

High

876531

LAR4B
La-related protein 4B

1

8

Small-scale

0.437

High

876538

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

12

High-throughput

0.437

High

876540

Q8BUJ0
Titin

1

16

Small-scale

0.437

High

876541

MT21E
Protein-lysine methyltransferase METTL21E

1

6

High-throughput

0.437

High

876544

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.437

High

876550

Q99JZ4
small monomeric GTPase

1

7

Small-scale

0.437

High

876560

CNN3
Calponin-3

1

3

Small-scale

0.437

High

876561

Q9DCC5
Cbx3 protein

1

7

Small-scale

0.437

High

876563

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

10

Small-scale

0.437

High

59460

A2AKD7
Alpha-1-syntrophin

1

9

High-throughput

0.407

High

205715

RB33B
Ras-related protein Rab-33B

1

3

High-throughput

0.407

High

771691

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

5

High-throughput

0.407

High

876513

CAV3
Caveolin-3

1

2

High-throughput

0.407

High

876543

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

4

High-throughput

0.407

High

876565

B9D1
B9 domain-containing protein 1

1

4

Small-scale

0.407

High

876542

GT251
Procollagen galactosyltransferase 1

1

0

Small-scale

0.249

Low

876564

ESTD
S-formylglutathione hydrolase

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025