Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.666

The method score is based on:

Property Details
Experiments 16169070, 31615977, 17184779
Identification Methods two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043066 - negative regulation of apoptotic process
GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 393
Hs

1 205
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024