HitPredict - High confidence protein-protein interactions

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: ETS1 (P14921)
Protein C-ets-1 (p54)
Gene: ETS1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	18374905, 24857950, 14586398, 15469934
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000976 - transcription cis-regulatory region binding GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific and 14 others more... GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0008285 - negative regulation of cell population proliferation GO:0010628 - positive regulation of gene expression GO:0042981 - regulation of apoptotic process GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046677 - response to antibiotic GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:1902895 - positive regulation of miRNA transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	393
Hs

1	441

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Last updated: 15 Jul 2024