Protein: LMNB2
Lamin-B2

Gene: LMNB2
Organism: Homo sapiens
Interactions: 229
UniProt ID: Q03252

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005635 - nuclear envelope
GO:0005652 - nuclear lamina
GO:0005882 - intermediate filament
GO:0006998 - nuclear envelope organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

385669

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

15

19

Small-scale

0.982

High

634413

LMNB1
Lamin-B1

14

19

Small-scale

0.982

High

1041978

LMNB2
Lamin-B2

3

20

High-throughput

0.843

High

837567

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

3

8

Small-scale

0.642

High

1041985

XRCC4
DNA repair protein XRCC4

1

2

High-throughput

0.618

High

285641

BAF
Barrier-to-autointegration factor

1

4

Small-scale

0.618

High

571935

TRI27
Zinc finger protein RFP

2

19

High-throughput

0.606

High

1042013

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

9

Small-scale

0.571

High

64530

CC88B
Coiled-coil domain-containing protein 88B

2

14

High-throughput

0.553

High

162988

OVOL1
Putative transcription factor Ovo-like 1

2

14

High-throughput

0.553

High

288395

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

17

High-throughput

0.553

High

764225

CAH8
Carbonic anhydrase-related protein

2

3

High-throughput

0.553

High

935493

MFAP1
Microfibrillar-associated protein 1

2

4

High-throughput

0.553

High

1007910

PO6F2
POU domain, class 6, transcription factor 2

2

8

High-throughput

0.553

High

1041981

GOGA2
Golgin subfamily A member 2

2

18

High-throughput

0.553

High

1042001

ZFHX3
Zinc finger homeobox protein 3

2

4

High-throughput

0.553

High

1042002

CDC37
Hsp90 co-chaperone Cdc37

2

2

High-throughput

0.553

High

1042005

T10IP
Testis-specific protein 10-interacting protein

2

2

High-throughput

0.553

High

1042011

ZC21C
Zinc finger C2HC domain-containing protein 1C

2

2

High-throughput

0.553

High

1042012

EFHC2
EF-hand domain-containing family member C2

2

2

High-throughput

0.553

High

1042050

CC120
Coiled-coil domain-containing protein 120

2

5

High-throughput

0.553

High

1042053

ASPP1
Apoptosis-stimulating of p53 protein 1

2

9

High-throughput

0.553

High

1042088

THAP1
THAP domain-containing protein 1

2

2

High-throughput

0.553

High

1042094

TFP11
Tuftelin-interacting protein 11

2

6

High-throughput

0.553

High

1042099

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

20

High-throughput

0.553

High

1042101

LZTS1
Leucine zipper putative tumor suppressor 1

2

20

High-throughput

0.553

High

1042104

AMOL2
Angiomotin-like protein 2

2

20

High-throughput

0.553

High

1042105

WASC3
WASH complex subunit 3

2

3

High-throughput

0.553

High

231391

PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

2

2

Small-scale

0.549

High

563654

CFTR
Cystic fibrosis transmembrane conductance regulator

2

15

High-throughput

0.549

High

655799

TBG1
Tubulin gamma-1 chain

1

3

High-throughput

0.536

High

1042006

TBB8
Tubulin beta-8 chain

1

2

High-throughput

0.536

High

1042092

RTEL1
Regulator of telomere elongation helicase 1

1

2

High-throughput

0.536

High

105790

APRIO
Alternative prion protein

2

8

High-throughput

0.533

High

241453

PRKN
E3 ubiquitin-protein ligase parkin

2

16

High-throughput

0.533

High

259827

BRD4
Bromodomain-containing protein 4

2

8

High-throughput

0.533

High

371819

MYC
Myc proto-oncogene protein

2

17

High-throughput

0.533

High

1042084

ANLN
Anillin

2

12

High-throughput

0.533

High

934494

TERA
Transitional endoplasmic reticulum ATPase

2

11

High-throughput

0.521

High

1042034

DOCK8
Dedicator of cytokinesis protein 8

2

2

High-throughput

0.521

High

1042070

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

2

11

High-throughput

0.521

High

1041980

SOX4
Transcription factor SOX-4

1

19

Small-scale

0.504

High

158431

RFXK
DNA-binding protein RFXANK

1

6

Small-scale

0.489

High

227508

SPOP
Speckle-type POZ protein

1

9

High-throughput

0.489

High

297198

PRAF3
PRA1 family protein 3

1

5

High-throughput

0.489

High

361225

SODC
Superoxide dismutase [Cu-Zn]

1

7

High-throughput

0.489

High

542469

TOP2A
DNA topoisomerase 2-alpha

1

5

High-throughput

0.489

High

608253

EGLN
Endoglin

1

1

High-throughput

0.489

High

611659

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

2

High-throughput

0.489

High

640858

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

2

High-throughput

0.489

High

724045

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

4

High-throughput

0.489

High

787987

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

8

High-throughput

0.489

High

854006

KI67
Proliferation marker protein Ki-67

1

14

High-throughput

0.489

High

884624

SYHM
Histidine--tRNA ligase, mitochondrial

1

1

High-throughput

0.489

High

908694

CCNH
Cyclin-H

1

3

High-throughput

0.489

High

938009

FOXA3
Hepatocyte nuclear factor 3-gamma

1

4

High-throughput

0.489

High

1041982

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

3

High-throughput

0.489

High

1041984

FOXL1
Forkhead box protein L1

1

4

High-throughput

0.489

High

1041987

PEX6
Peroxisomal ATPase PEX6

1

11

High-throughput

0.489

High

1041992

DIP2A
Disco-interacting protein 2 homolog A

1

3

High-throughput

0.489

High

1041996

RHEB
GTP-binding protein Rheb

1

6

High-throughput

0.489

High

1041998

MARE1
Microtubule-associated protein RP/EB family member 1

1

2

High-throughput

0.489

High

1042014

DDX59
Probable ATP-dependent RNA helicase DDX59

1

16

High-throughput

0.489

High

1042015

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.489

High

1042022

COX15
Heme A synthase COX15

1

1

High-throughput

0.489

High

1042023

KDM3B
Lysine-specific demethylase 3B

1

5

High-throughput

0.489

High

1042026

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

12

High-throughput

0.489

High

1042030

DHX40
Probable ATP-dependent RNA helicase DHX40

1

7

High-throughput

0.489

High

1042031

DDX51
ATP-dependent RNA helicase DDX51

1

12

High-throughput

0.489

High

1042033

PHC3
Polyhomeotic-like protein 3

1

5

High-throughput

0.489

High

1042036

LEO1
RNA polymerase-associated protein LEO1

1

1

High-throughput

0.489

High

1042040

ING5
Inhibitor of growth protein 5

1

2

High-throughput

0.489

High

1042051

REXO5
RNA exonuclease 5

1

6

High-throughput

0.489

High

1042054

NSUN5
28S rRNA

1

3

High-throughput

0.489

High

1042063

AFG2B
ATPase family gene 2 protein homolog B

1

11

High-throughput

0.489

High

1042080

ANRA2
Ankyrin repeat family A protein 2

1

9

Small-scale

0.489

High

1042087

DDX28
Probable ATP-dependent RNA helicase DDX28

1

15

High-throughput

0.489

High

285226

EED
Polycomb protein EED

1

15

High-throughput

0.479

High

581004

RAC2
Ras-related C3 botulinum toxin substrate 2

1

14

High-throughput

0.479

High

664716

CCND1
G1/S-specific cyclin-D1

1

5

High-throughput

0.479

High

894693

EMD
Emerin

1

4

High-throughput

0.479

High

904625

MECP2
Methyl-CpG-binding protein 2

1

10

High-throughput

0.479

High

955081

CDC42
Cell division control protein 42 homolog

1

15

High-throughput

0.479

High

1042000

EZH2
Histone-lysine N-methyltransferase EZH2

1

17

High-throughput

0.479

High

1042016

RN123
E3 ubiquitin-protein ligase RNF123

1

11

High-throughput

0.479

High

1042044

LRC59
Leucine-rich repeat-containing protein 59

1

4

High-throughput

0.479

High

1042052

DNJC1
DnaJ homolog subfamily C member 1

1

14

High-throughput

0.479

High

1031345

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.470

High

1042038

CLC4D
C-type lectin domain family 4 member D

1

6

High-throughput

0.470

High

1042055

GP101
Probable G-protein coupled receptor 101

1

3

High-throughput

0.470

High

1042077

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

10

High-throughput

0.470

High

1042100

CLC4E
C-type lectin domain family 4 member E

1

6

High-throughput

0.470

High

59913

A2BDD9
AMOT protein

1

11

High-throughput

0.470

High

1041979

Q05BL1
TP53BP2 protein

1

10

High-throughput

0.470

High

1042007

Q4G0R1
PIBF1 protein

1

2

High-throughput

0.470

High

404770

PRIO
Major prion protein

1

1

High-throughput

0.445

High

336408

SVIL
Supervillin

1

2

Small-scale

0.439

High

1041989

ASPP2
Apoptosis-stimulating of p53 protein 2

1

12

High-throughput

0.439

High

1042008

AMOT
Angiomotin

1

17

High-throughput

0.439

High

1042039

PIBF1
Progesterone-induced-blocking factor 1

1

2

High-throughput

0.439

High

51071

PKHG3
Pleckstrin homology domain-containing family G member 3

1

9

High-throughput

0.437

High

126560

RHOD
Rho-related GTP-binding protein RhoD

1

19

High-throughput

0.437

High

157265

CTRO
Citron Rho-interacting kinase

1

14

High-throughput

0.437

High

188867

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.437

High

222959

PRC1
Protein regulator of cytokinesis 1

1

9

High-throughput

0.437

High

247841

NUPR1
Nuclear protein 1

1

4

High-throughput

0.437

High

272094

OBSL1
Obscurin-like protein 1

1

13

High-throughput

0.437

High

274541

DNJB6
DnaJ homolog subfamily B member 6

1

3

High-throughput

0.437

High

298506

SPF30
Survival of motor neuron-related-splicing factor 30

1

1

High-throughput

0.437

High

315486

RECQ4
ATP-dependent DNA helicase Q4

1

19

High-throughput

0.437

High

330887

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.437

High

342836

HERC2
E3 ubiquitin-protein ligase HERC2

1

9

High-throughput

0.437

High

345696

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

High-throughput

0.437

High

411773

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.437

High

417390

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.437

High

418078

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.437

High

466214

RHOC
Rho-related GTP-binding protein RhoC

1

14

High-throughput

0.437

High

473930

NFIC
Nuclear factor 1 C-type

1

7

High-throughput

0.437

High

560372

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.437

High

611088

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

8

High-throughput

0.437

High

692936

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.437

High

731217

STIP1
Stress-induced-phosphoprotein 1

1

7

High-throughput

0.437

High

765424

BMI1
Polycomb complex protein BMI-1

1

20

Small-scale

0.437

High

828644

MDHC
Malate dehydrogenase, cytoplasmic

1

5

High-throughput

0.437

High

830596

CCNF
Cyclin-F

1

4

High-throughput

0.437

High

847507

SSRA
Translocon-associated protein subunit alpha

1

3

High-throughput

0.437

High

872232

SOX2
Transcription factor SOX-2

1

14

High-throughput

0.437

High

910023

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.437

High

929907

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

9

High-throughput

0.437

High

951109

SC61B
Protein transport protein Sec61 subunit beta

1

3

High-throughput

0.437

High

953404

RAC3
Ras-related C3 botulinum toxin substrate 3

1

15

High-throughput

0.437

High

957333

UBC12
NEDD8-conjugating enzyme Ubc12

1

5

High-throughput

0.437

High

959136

ABCE1
ATP-binding cassette sub-family E member 1

1

4

High-throughput

0.437

High

961975

RHOA
Transforming protein RhoA

1

16

High-throughput

0.437

High

964870

WDR5
WD repeat-containing protein 5

1

9

High-throughput

0.437

High

970367

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

8

High-throughput

0.437

High

979534

H4
Histone H4

1

5

High-throughput

0.437

High

988302

RAC1
Ras-related C3 botulinum toxin substrate 1

1

15

High-throughput

0.437

High

1004469

RNF4
E3 ubiquitin-protein ligase RNF4

1

9

High-throughput

0.437

High

1015382

RHOG
Rho-related GTP-binding protein RhoG

1

14

High-throughput

0.437

High

1016791

H33
Histone H3.3

1

8

High-throughput

0.437

High

1035549

KIF23
Kinesin-like protein KIF23

1

16

High-throughput

0.437

High

1041983

ARHG5
Rho guanine nucleotide exchange factor 5

1

13

High-throughput

0.437

High

1041986

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.437

High

1041988

CUL4A
Cullin-4A

1

20

High-throughput

0.437

High

1041991

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

6

High-throughput

0.437

High

1041993

CUL7
Cullin-7

1

10

High-throughput

0.437

High

1041995

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.437

High

1041997

RHOH
Rho-related GTP-binding protein RhoH

1

16

High-throughput

0.437

High

1042003

RHG44
Rho GTPase-activating protein 44

1

16

High-throughput

0.437

High

1042004

ANR55
Ankyrin repeat domain-containing protein 55

1

8

High-throughput

0.437

High

1042009

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

12

High-throughput

0.437

High

1042010

MIDN
Midnolin

1

5

High-throughput

0.437

High

1042017

VIR
Protein virilizer homolog

1

5

High-throughput

0.437

High

1042018

RICTR
Rapamycin-insensitive companion of mTOR

1

5

High-throughput

0.437

High

1042019

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

1042021

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1042024

SLN11
Schlafen family member 11

1

4

High-throughput

0.437

High

1042025

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1042027

ZN598
E3 ubiquitin-protein ligase ZNF598

1

6

High-throughput

0.437

High

1042028

ZCH18
Zinc finger CCCH domain-containing protein 18

1

17

High-throughput

0.437

High

1042032

DHB11
Estradiol 17-beta-dehydrogenase 11

1

4

High-throughput

0.437

High

1042035

DEP1B
DEP domain-containing protein 1B

1

6

High-throughput

0.437

High

1042041

ESR2
Estrogen receptor beta

1

20

High-throughput

0.437

High

1042042

ARHG1
Rho guanine nucleotide exchange factor 1

1

11

High-throughput

0.437

High

1042043

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

High-throughput

0.437

High

1042045

CLUA1
Clusterin-associated protein 1

1

2

High-throughput

0.437

High

1042046

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.437

High

1042047

CHM4C
Charged multivesicular body protein 4c

1

8

High-throughput

0.437

High

1042048

GASP2
G-protein coupled receptor-associated sorting protein 2

1

1

High-throughput

0.437

High

1042056

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

2

High-throughput

0.437

High

1042057

CIC
Protein capicua homolog

1

20

High-throughput

0.437

High

1042058

RANB9
Ran-binding protein 9

1

11

High-throughput

0.437

High

1042059

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

1042060

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.437

High

1042062

FOXB1
Forkhead box protein B1

1

4

High-throughput

0.437

High

1042065

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

14

High-throughput

0.437

High

1042067

FACD2
Fanconi anemia group D2 protein

1

13

High-throughput

0.437

High

1042068

LNP
Endoplasmic reticulum junction formation protein lunapark

1

1

High-throughput

0.437

High

1042069

CCDC8
Coiled-coil domain-containing protein 8

1

7

High-throughput

0.437

High

1042071

DJC25
DnaJ homolog subfamily C member 25

1

10

High-throughput

0.437

High

1042072

GAN
Gigaxonin

1

13

High-throughput

0.437

High

1042073

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

3

High-throughput

0.437

High

1042074

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

14

Small-scale

0.437

High

1042075

RHOJ
Rho-related GTP-binding protein RhoJ

1

15

High-throughput

0.437

High

1042076

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.437

High

1042078

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.437

High

1042079

AKTIP
AKT-interacting protein

1

4

Small-scale

0.437

High

1042082

RHOF
Rho-related GTP-binding protein RhoF

1

18

High-throughput

0.437

High

1042085

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.437

High

1042086

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

7

High-throughput

0.437

High

1042089

TSAP1
tRNA selenocysteine 1-associated protein 1

1

2

High-throughput

0.437

High

1042090

HYPK
Huntingtin-interacting protein K

1

1

Small-scale

0.437

High

1042091

ELOV5
Very long chain fatty acid elongase 5

1

3

High-throughput

0.437

High

1042093

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.437

High

1042096

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.437

High

1042097

SEC63
Translocation protein SEC63 homolog

1

8

High-throughput

0.437

High

1042102

DJC16
DnaJ homolog subfamily C member 16

1

6

High-throughput

0.437

High

1042103

FND3A
Fibronectin type-III domain-containing protein 3A

1

13

High-throughput

0.437

High

1042106

TRRAP
Transformation/transcription domain-associated protein

1

4

High-throughput

0.437

High

1042107

LOXL2
Lysyl oxidase homolog 2

1

5

High-throughput

0.437

High

1042108

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.437

High

87436

OSCRI
SCRIB overlapping open reading frame protein

1

3

High-throughput

0.407

High

429760

JUN
Transcription factor Jun

1

15

High-throughput

0.407

High

529667

TAU
Microtubule-associated protein tau

1

18

High-throughput

0.407

High

675469

TYY1
Transcriptional repressor protein YY1

1

17

Small-scale

0.407

High

756156

MCM7
DNA replication licensing factor MCM7

1

11

Small-scale

0.407

High

1041999

UT2
Urea transporter 2

1

2

High-throughput

0.407

High

1042020

CLC4G
C-type lectin domain family 4 member G

1

7

Small-scale

0.407

High

1042061

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

4

High-throughput

0.407

High

1042066

S12A9
Solute carrier family 12 member 9

1

2

High-throughput

0.407

High

1042095

SL9A2
Sodium/hydrogen exchanger 2

1

3

High-throughput

0.407

High

881701

FNTB
Protein farnesyltransferase subunit beta

3

0

High-throughput

0.347

High

464258

FUMH
Fumarate hydratase, mitochondrial

2

0

High-throughput

0.316

High

649880

ADRO
NADPH:adrenodoxin oxidoreductase, mitochondrial

1

0

High-throughput

0.279

Low

881653

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

0

High-throughput

0.279

Low

908736

MAT1
CDK-activating kinase assembly factor MAT1

1

0

High-throughput

0.279

Low

1041990

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.279

Low

1042029

PALB2
Partner and localizer of BRCA2

1

0

High-throughput

0.279

Low

1042037

SEN15
tRNA-splicing endonuclease subunit Sen15

1

0

High-throughput

0.279

Low

1042049

TRM2B
tRNA

1

0

High-throughput

0.279

Low

1042064

GTPB2
GTP-binding protein 2

1

0

High-throughput

0.279

Low

1042083

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

0

High-throughput

0.279

Low

1042098

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.279

Low

69726

SFI1
Protein SFI1 homolog

1

0

High-throughput

0.269

Low

1041994

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.269

Low

352409

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

1042081

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025