HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: NR4A1 (P22736)
Nuclear receptor subfamily 4immunitygroup A member 1 (Early response protein NAK1) (Nuclear hormone receptor NUR/77) (Nur77) (Orphan nuclear receptor HMR) (Orphan nuclear receptor TR3) (ST-59) (Testicular receptor 3)
Gene: NR4A1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

The method score is based on:

Property	Details
Experiments	23071566, 17139261
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid array
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0003677 - DNA binding and 10 others more... GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II GO:0008270 - zinc ion binding GO:0043065 - positive regulation of apoptotic process GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046982 - protein heterodimerization activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	393
Hs

1	598

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024