Protein: K1C14
Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)

Gene: K1C14, KRT14
Organism: Homo sapiens
Interactions: 180
UniProt ID: P02533

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

359299

K2C5
Keratin, type II cytoskeletal 5

1

20

Small-scale

0.809

High

213924

KRT86
Keratin, type II cuticular Hb6

2

20

High-throughput

0.783

High

359288

K2C1
Keratin, type II cytoskeletal 1

2

20

High-throughput

0.783

High

359297

K2C3
Keratin, type II cytoskeletal 3

2

20

High-throughput

0.783

High

359310

PERI
Peripherin

2

20

High-throughput

0.783

High

359315

K2C6C
Keratin, type II cytoskeletal 6C

2

20

High-throughput

0.783

High

359340

BFSP2
Phakinin

2

20

High-throughput

0.783

High

359348

KRT81
Keratin, type II cuticular Hb1

2

20

High-throughput

0.783

High

359351

K2C72
Keratin, type II cytoskeletal 72

2

20

High-throughput

0.783

High

359368

K2C79
Keratin, type II cytoskeletal 79

2

20

High-throughput

0.783

High

359370

K2C80
Keratin, type II cytoskeletal 80

2

20

High-throughput

0.783

High

359381

K2C78
Keratin, type II cytoskeletal 78

2

20

High-throughput

0.783

High

359291

NFL
Neurofilament light polypeptide

1

20

High-throughput

0.691

High

359292

NFM
Neurofilament medium polypeptide

1

20

High-throughput

0.691

High

359360

AINX
Alpha-internexin

1

20

High-throughput

0.691

High

359417

SYNCI
Syncoilin

1

20

High-throughput

0.691

High

359285

K1C14
Keratin, type I cytoskeletal 14

1

20

Small-scale

0.647

High

359355

PLEC
Plectin

2

20

High-throughput

0.621

High

359290

K2C8
Keratin, type II cytoskeletal 8

1

20

High-throughput

0.621

High

359330

KRT85
Keratin, type II cuticular Hb5

1

20

High-throughput

0.621

High

359378

K2C1B
Keratin, type II cytoskeletal 1b

1

20

High-throughput

0.621

High

359335

K1C17
Keratin, type I cytoskeletal 17

1

20

High-throughput

0.618

High

132705

SDCB1
Syntenin-1

2

6

High-throughput

0.606

High

159833

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

20

High-throughput

0.606

High

204269

MS18B
Protein Mis18-beta

2

9

High-throughput

0.606

High

330051

DRC4
Dynein regulatory complex subunit 4

2

4

High-throughput

0.606

High

359322

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

20

High-throughput

0.606

High

359362

PUS10
tRNA pseudouridine synthase Pus10

2

1

High-throughput

0.606

High

359383

USBP1
Harmonin-binding protein USHBP1

2

19

High-throughput

0.606

High

359395

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

2

10

High-throughput

0.606

High

359404

KIFC3
Kinesin-like protein KIFC3

2

15

High-throughput

0.606

High

359423

ABI2
Abl interactor 2

2

20

High-throughput

0.606

High

359425

ABI3
ABI gene family member 3

2

20

High-throughput

0.606

High

255411

OBSL1
Obscurin-like protein 1

2

9

High-throughput

0.584

High

359289

P53
Cellular tumor antigen p53

2

8

Small-scale

0.584

High

359413

CCDC8
Coiled-coil domain-containing protein 8

2

4

High-throughput

0.584

High

359345

PKP1
Plakophilin-1

1

8

Small-scale

0.561

High

359390

CTTB2
Cortactin-binding protein 2

2

4

High-throughput

0.553

High

359411

ENKD1
Enkurin domain-containing protein 1

2

3

High-throughput

0.553

High

359296

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.541

High

359304

APC
Adenomatous polyposis coli protein

1

8

High-throughput

0.541

High

359286

ALBU
Albumin

1

7

High-throughput

0.536

High

359308

IF4A3
Eukaryotic initiation factor 4A-III

1

16

High-throughput

0.536

High

359309

TXLNA
Alpha-taxilin

1

20

High-throughput

0.536

High

359323

EPIPL
Epiplakin

1

20

High-throughput

0.536

High

359334

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.536

High

359341

CUL1
Cullin-1

1

20

High-throughput

0.536

High

359342

CUL2
Cullin-2

1

20

High-throughput

0.536

High

359343

CUL3
Cullin-3

1

20

High-throughput

0.536

High

359344

CUL4B
Cullin-4B

1

20

High-throughput

0.536

High

359352

FL2D
Pre-mRNA-splicing regulator WTAP

1

8

High-throughput

0.536

High

359356

PCM1
Pericentriolar material 1 protein

1

8

High-throughput

0.536

High

359358

NEDD8
NEDD8

1

6

High-throughput

0.536

High

359361

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

14

High-throughput

0.536

High

359379

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

12

High-throughput

0.536

High

359380

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

7

High-throughput

0.536

High

359387

RIN3
Ras and Rab interactor 3

1

3

High-throughput

0.536

High

359392

CSN5
COP9 signalosome complex subunit 5

1

17

High-throughput

0.536

High

359394

CUL5
Cullin-5

1

20

High-throughput

0.536

High

359415

GAN
Gigaxonin

1

14

High-throughput

0.536

High

359419

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

12

High-throughput

0.536

High

359424

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

11

High-throughput

0.536

High

359403

TCHP
Trichoplein keratin filament-binding protein

1

16

Small-scale

0.527

High

359389

CCNB3
G2/mitotic-specific cyclin-B3

1

1

High-throughput

0.515

High

359405

SARG
Specifically androgen-regulated gene protein

1

0

High-throughput

0.493

High

359333

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

10

High-throughput

0.484

High

359364

AMOT
Angiomotin

1

20

High-throughput

0.481

High

124710

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

9

Small-scale

0.479

High

129154

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.479

High

133821

DDX3X
ATP-dependent RNA helicase DDX3X

1

7

Small-scale

0.479

High

176336

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

11

High-throughput

0.479

High

197171

SERA
D-3-phosphoglycerate dehydrogenase

1

7

Small-scale

0.479

High

214019

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

226212

PRKN
E3 ubiquitin-protein ligase parkin

1

15

High-throughput

0.479

High

241928

PAGE4
P antigen family member 4

1

1

High-throughput

0.479

High

260435

PITX3
Pituitary homeobox 3

1

9

Small-scale

0.479

High

277870

PIAS1
E3 SUMO-protein ligase PIAS1

1

3

High-throughput

0.479

High

282456

RNF8
E3 ubiquitin-protein ligase RNF8

1

17

High-throughput

0.479

High

298030

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

301514

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.479

High

302761

HEXI1
Protein HEXIM1

1

20

High-throughput

0.479

High

312438

ARI2
E3 ubiquitin-protein ligase ARIH2

1

19

High-throughput

0.479

High

345636

MYC
Myc proto-oncogene protein

1

13

High-throughput

0.479

High

359287

MYCN
N-myc proto-oncogene protein

1

13

High-throughput

0.479

High

359293

F16P1
Fructose-1,6-bisphosphatase 1

1

6

High-throughput

0.479

High

359294

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

14

High-throughput

0.479

High

359298

CFTR
Cystic fibrosis transmembrane conductance regulator

1

20

High-throughput

0.479

High

359300

EGR1
Early growth response protein 1

1

6

High-throughput

0.479

High

359301

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

359303

CBL
E3 ubiquitin-protein ligase CBL

1

11

High-throughput

0.479

High

359305

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.479

High

359306

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.479

High

359307

TRI23
E3 ubiquitin-protein ligase TRIM23

1

12

High-throughput

0.479

High

359311

EPS15
Epidermal growth factor receptor substrate 15

1

20

High-throughput

0.479

High

359312

NKX21
Homeobox protein Nkx-2.1

1

2

High-throughput

0.479

High

359313

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

359314

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

359316

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

3

High-throughput

0.479

High

359317

ARL4D
ADP-ribosylation factor-like protein 4D

1

10

High-throughput

0.479

High

359320

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.479

High

359321

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.479

High

359326

MGN
Protein mago nashi homolog

1

4

High-throughput

0.479

High

359327

WDR5
WD repeat-containing protein 5

1

5

High-throughput

0.479

High

359328

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

13

High-throughput

0.479

High

359329

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

359331

ARF1
ADP-ribosylation factor 1

1

6

High-throughput

0.479

High

359332

ARF5
ADP-ribosylation factor 5

1

6

High-throughput

0.479

High

359337

TFCP2
Alpha-globin transcription factor CP2

1

8

High-throughput

0.479

High

359338

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.479

High

359339

TRI26
Tripartite motif-containing protein 26

1

15

Small-scale

0.479

High

359346

DX39B
Spliceosome RNA helicase DDX39B

1

20

High-throughput

0.479

High

359349

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.479

High

359350

CUL7
Cullin-7

1

6

High-throughput

0.479

High

359353

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

9

High-throughput

0.479

High

359354

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

19

High-throughput

0.479

High

359359

EZH2
Histone-lysine N-methyltransferase EZH2

1

14

High-throughput

0.479

High

359363

LARP7
La-related protein 7

1

16

High-throughput

0.479

High

359365

MIDN
Midnolin

1

3

High-throughput

0.479

High

359369

VIR
Protein virilizer homolog

1

5

High-throughput

0.479

High

359371

PRP8
Pre-mRNA-processing-splicing factor 8

1

11

High-throughput

0.479

High

359373

RICTR
Rapamycin-insensitive companion of mTOR

1

6

High-throughput

0.479

High

359375

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

7

High-throughput

0.479

High

359376

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

359377

MEPCE
7SK snRNA methylphosphate capping enzyme

1

15

High-throughput

0.479

High

359382

RHG24
Rho GTPase-activating protein 24

1

6

High-throughput

0.479

High

359386

TNIP2
TNFAIP3-interacting protein 2

1

8

High-throughput

0.479

High

359388

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

20

High-throughput

0.479

High

359391

HDAC2
Histone deacetylase 2

1

13

High-throughput

0.479

High

359396

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

8

Small-scale

0.479

High

359397

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.479

High

359398

AP2M1
AP-2 complex subunit mu

1

8

High-throughput

0.479

High

359399

RNF31
E3 ubiquitin-protein ligase RNF31

1

17

High-throughput

0.479

High

359400

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.479

High

359402

PKP2
Plakophilin-2

1

16

Small-scale

0.479

High

359406

ACE2
Angiotensin-converting enzyme 2

1

8

High-throughput

0.479

High

359407

TRI31
E3 ubiquitin-protein ligase TRIM31

1

15

High-throughput

0.479

High

359408

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

6

High-throughput

0.479

High

359414

RN208
RING finger protein 208

1

20

Small-scale

0.479

High

359420

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

15

High-throughput

0.479

High

359421

ANLN
Anillin

1

12

High-throughput

0.479

High

359422

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

359426

HDAC6
Histone deacetylase 6

1

19

High-throughput

0.479

High

359427

KS6B2
Ribosomal protein S6 kinase beta-2

1

8

High-throughput

0.479

High

359428

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

359429

MBD1
Methyl-CpG-binding domain protein 1

1

5

Small-scale

0.479

High

359430

FZR1
Fizzy-related protein homolog

1

16

High-throughput

0.479

High

359431

FAF1
FAS-associated factor 1

1

2

High-throughput

0.479

High

57663

A2BDD9
AMOT protein

1

20

High-throughput

0.470

High

117332

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.458

High

359324

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

359357

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

3

Small-scale

0.457

High

305883

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.445

High

337730

EGFR
Epidermal growth factor receptor

1

11

Small-scale

0.445

High

353599

IGHG1
Immunoglobulin heavy constant gamma 1

1

10

High-throughput

0.445

High

354016

IGHA1
Immunoglobulin heavy constant alpha 1

1

10

High-throughput

0.445

High

359295

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

359325

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

359347

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.445

High

359367

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.445

High

359409

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

20

High-throughput

0.445

High

359412

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

359416

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

20

High-throughput

0.445

High

181026

INSI1
Insulin-induced gene 1 protein

1

3

High-throughput

0.437

High

359302

EFNA1
Ephrin-A1

1

20

High-throughput

0.437

High

359318

EFNA3
Ephrin-A3

1

20

High-throughput

0.437

High

359319

EFNA4
Ephrin-A4

1

20

High-throughput

0.437

High

359366

EMC4
ER membrane protein complex subunit 4

1

4

High-throughput

0.437

High

359372

FBX42
F-box only protein 42

1

2

High-throughput

0.437

High

359374

LRC31
Leucine-rich repeat-containing protein 31

1

11

High-throughput

0.437

High

359384

ARL10
ADP-ribosylation factor-like protein 10

1

10

High-throughput

0.437

High

359393

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

3

High-throughput

0.437

High

359401

ARL5B
ADP-ribosylation factor-like protein 5B

1

7

High-throughput

0.437

High

359410

DDX24
ATP-dependent RNA helicase DDX24

1

20

High-throughput

0.437

High

359418

RC3H2
Roquin-2

1

19

High-throughput

0.437

High

359432

AAR2
Protein AAR2 homolog

1

6

High-throughput

0.437

High

135193

E2F3
Transcription factor E2F3

1

0

Small-scale

0.426

High

359336

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

Small-scale

0.426

High

876

SIM26
Small integral membrane protein 26

1

5

High-throughput

0.407

High

359385

MOT11
Monocarboxylate transporter 11

1

5

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024