HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: MCM3 (P25205)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)
Gene: MCM3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32807901, 38580884
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005813 - centrosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 808
+	Hs
		386314 P53_HUMAN (1-393): 0: 619: 100.00		MCM2_HUMAN (10-721): 0: 707: 30.62
+	Hs
		386729 P53_HUMAN (1-393): 0: 619: 100.00		MCM6_HUMAN (2-800): 0: 688: 26.50
+	Hs
		386196 P53_HUMAN (1-393): 0: 619: 100.00		MCM5_HUMAN (9-713): 0: 685: 28.92
+	Hs
		386195 P53_HUMAN (1-393): 0: 619: 100.00		MCM4_HUMAN (9-739): 0: 661: 28.03
+	Hs
		386197 P53_HUMAN (1-393): 0: 619: 100.00		MCM7_HUMAN (10-669): 0: 650: 31.62