HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	22653443
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0045892 - negative regulation of DNA-templated transcription GO:0071889 - 14-3-3 protein binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 245
+	Hs
		386446 P53_HUMAN (1-393): 0: 619: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		386482 P53_HUMAN (1-393): 0: 619: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		386182 P53_HUMAN (1-393): 0: 619: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		386183 P53_HUMAN (1-393): 0: 619: 100.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		386438 P53_HUMAN (1-393): 0: 619: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Mm
		250864 P53_MOUSE (1-393): 0: 589: 77.35		1433S_MOUSE (1-232): 2e-106: 309: 72.65
+	Hs
		684322 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85