Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.977 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23267009, 15489903, 9121469, 11751427, 32807901, 34795231, 16234232, 8663296, 37827155, 15735006 |
| Identification Methods | pull down, affinity chromatography technology, proximity labelling technology, x-ray crystallography, enzyme linked immunosorbent assay |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Rep-A_N~TAD2 |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006289 - nucleotide-excision repair GO:0006974 - DNA damage response GO:0016605 - PML body and 1 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
