HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	35140242, 38580884
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006302 - double-strand break repair GO:0006974 - DNA damage response and 1 others more... GO:0035861 - site of double-strand break
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1312
+	Hs
		386212 P53_HUMAN (1-393): 0: 619: 100.00		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		387710 P53_HUMAN (1-393): 0: 619: 100.00		MYH13_HUMAN (524-1245): 6.07e-22: 105: 10.56
+	Hs
		387815 P53_HUMAN (1-393): 0: 619: 100.00		MYH4_HUMAN (785-1235): 1.33e-14: 81.7: 12.88
+	Hs
		386037 P53_HUMAN (1-393): 0: 619: 100.00		DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71
+	Hs
		148271 P53_HUMAN (1-393): 0: 619: 100.00		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15