Protein: PRTN3
Myeloblastin (EC 3.4.21.76) (AGP7) (C-ANCA antigen) (Leukocyte proteinase 3) (PR-3) (PR3) (Neutrophil proteinase 4) (NP-4) (P29) (Wegener autoantigen)

Gene: PRTN3
Organism: Homo sapiens
Interactions: 87
UniProt ID: P24158

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

621770

ILEU
Leukocyte elastase inhibitor

2

20

Small-scale

0.799

High

198402

KLK10
Kallikrein-10

1

16

High-throughput

0.691

High

280206

CBPD
Carboxypeptidase D

1

6

High-throughput

0.691

High

426510

KLK3
Prostate-specific antigen

1

15

High-throughput

0.691

High

488125

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

14

High-throughput

0.691

High

566852

ITA2
Integrin alpha-2

1

13

High-throughput

0.691

High

621769

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

14

High-throughput

0.691

High

621786

PRSS8
Prostasin

1

13

High-throughput

0.691

High

621804

LRC17
Leucine-rich repeat-containing protein 17

1

10

High-throughput

0.691

High

621815

EGFL8
Epidermal growth factor-like protein 8

1

20

High-throughput

0.691

High

344162

A1AT
Alpha-1-antitrypsin

1

20

Small-scale

0.647

High

506100

ITAM
Integrin alpha-M

1

13

Small-scale

0.618

High

621537

IL32
Interleukin-32

1

0

Small-scale

0.572

High

129466

MANBA
Beta-mannosidase

1

6

High-throughput

0.536

High

152253

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

20

High-throughput

0.536

High

240693

USO1
General vesicular transport factor p115

1

7

High-throughput

0.536

High

381126

TBB4A
Tubulin beta-4A chain

1

20

High-throughput

0.536

High

428023

TBB5
Tubulin beta chain

1

20

High-throughput

0.536

High

501694

BIP
Endoplasmic reticulum chaperone BiP

1

13

High-throughput

0.536

High

574497

ITB5
Integrin beta-5

1

7

High-throughput

0.536

High

607880

FGFR4
Fibroblast growth factor receptor 4

1

19

High-throughput

0.536

High

609179

FGFR3
Fibroblast growth factor receptor 3

1

18

High-throughput

0.536

High

621767

DCK
Deoxycytidine kinase

1

2

High-throughput

0.536

High

621771

CCR1
C-C chemokine receptor type 1

1

7

High-throughput

0.536

High

621772

STAT3
Signal transducer and activator of transcription 3

1

3

High-throughput

0.536

High

621775

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

2

High-throughput

0.536

High

621776

TBA4A
Tubulin alpha-4A chain

1

20

High-throughput

0.536

High

621778

XIAP
E3 ubiquitin-protein ligase XIAP

1

9

High-throughput

0.536

High

621780

BIRC2
Baculoviral IAP repeat-containing protein 2

1

6

High-throughput

0.536

High

621784

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

3

High-throughput

0.536

High

621785

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.536

High

621789

TBB8
Tubulin beta-8 chain

1

20

High-throughput

0.536

High

621791

KLH22
Kelch-like protein 22

1

2

High-throughput

0.536

High

621793

TGO1
Transport and Golgi organization protein 1 homolog

1

7

High-throughput

0.536

High

621797

POTEE
POTE ankyrin domain family member E

1

6

High-throughput

0.536

High

621799

TBA1A
Tubulin alpha-1A chain

1

20

High-throughput

0.536

High

621800

AGRG6
Adhesion G-protein coupled receptor G6

1

12

High-throughput

0.536

High

621801

FRAS1
Extracellular matrix organizing protein FRAS1

1

20

High-throughput

0.536

High

621805

NLGN2
Neuroligin-2

1

1

High-throughput

0.536

High

621806

RHBL4
Rhomboid-related protein 4

1

5

High-throughput

0.536

High

621811

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

5

High-throughput

0.536

High

621812

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

3

High-throughput

0.536

High

621817

ERP44
Endoplasmic reticulum resident protein 44

1

11

High-throughput

0.536

High

621818

TMM59
Transmembrane protein 59

1

2

High-throughput

0.536

High

621821

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.536

High

621823

BIRC6
Baculoviral IAP repeat-containing protein 6

1

4

High-throughput

0.536

High

621824

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

6

High-throughput

0.536

High

621825

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

18

High-throughput

0.536

High

621777

SMAD3
Mothers against decapentaplegic homolog 3

1

5

Small-scale

0.515

High

301073

FBX21
F-box only protein 21

1

0

High-throughput

0.513

High

621773

DHYS
Deoxyhypusine synthase

1

0

High-throughput

0.513

High

621782

PUM1
Pumilio homolog 1

1

0

High-throughput

0.513

High

621788

QRIC1
Transcriptional regulator QRICH1

1

0

High-throughput

0.513

High

621792

SPIN4
Spindlin-4

1

0

High-throughput

0.513

High

621795

LYPL1
Lysophospholipase-like protein 1

1

0

High-throughput

0.513

High

621820

SIL1
Nucleotide exchange factor SIL1

1

0

High-throughput

0.513

High

621827

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.513

High

548779

ELN
Elastin

1

13

Small-scale

0.501

High

621768

PROP
Properdin

1

16

Small-scale

0.501

High

621774

CAMP
Cathelicidin antimicrobial peptide

1

2

Small-scale

0.501

High

129374

GOLI4
Golgi integral membrane protein 4

1

6

High-throughput

0.489

High

621779

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.489

High

621783

SPCS2
Signal peptidase complex subunit 2

1

3

High-throughput

0.489

High

621787

ISX
Intestine-specific homeobox

1

3

High-throughput

0.489

High

621790

FUT11
Alpha-(1,3)-fucosyltransferase 11

1

3

High-throughput

0.489

High

621794

TMM69
Transmembrane protein 69

1

1

High-throughput

0.489

High

621798

NFXL1
NF-X1-type zinc finger protein NFXL1

1

13

High-throughput

0.489

High

621802

ELOA2
Elongin-A2

1

4

High-throughput

0.489

High

621803

CA174
UPF0688 protein C1orf174

1

1

High-throughput

0.489

High

621808

CCD47
PAT complex subunit CCDC47

1

2

High-throughput

0.489

High

621809

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

6

High-throughput

0.489

High

621810

PF21B
PHD finger protein 21B

1

6

High-throughput

0.489

High

621813

SMIM8
Small integral membrane protein 8

1

1

High-throughput

0.489

High

621814

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

10

High-throughput

0.489

High

621816

TBA1C
Tubulin alpha-1C chain

1

20

High-throughput

0.489

High

621822

CP343
Cytochrome P450 3A43

1

1

High-throughput

0.489

High

320087

CXL14
C-X-C motif chemokine 14

1

0

Small-scale

0.480

High

621781

IL18
Interleukin-18

1

0

Small-scale

0.480

High

255511

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.479

High

364650

TRFL
Lactotransferrin

1

3

High-throughput

0.479

High

398170

PERM
Myeloperoxidase

1

1

High-throughput

0.479

High

621807

ESR2
Estrogen receptor beta

1

8

High-throughput

0.479

High

256214

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

6

High-throughput

0.437

High

575274

EGR1
Early growth response protein 1

1

1

High-throughput

0.437

High

621796

ANR40
Ankyrin repeat domain-containing protein 40

1

0

High-throughput

0.279

Low

621819

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.279

Low

621826

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024