Interactor 1: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Interactor 2: ACHA7 (P36544)
Neuronal acetylcholine receptor subunit alpha-7 (nAChR7) (Nicotinic acetylcholine receptor subunit alpha-7)
Gene: CHRNA7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 28750690
Identification Methods solid phase assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001540 - amyloid-beta binding
GO:0005886 - plasma membrane
GO:0006874 - intracellular calcium ion homeostasis
GO:0016020 - membrane
GO:0030425 - dendrite
and 5 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 317
Hs

1 502
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025