HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TRIM8 (Q9BZR9)
E3 ubiquitin-protein ligase TRIM8 (EC 2.3.2.27) (Glioblastoma-expressed RING finger protein) (RING finger protein 27) (RING-type E3 ubiquitin transferase TRIM8) (Tripartite motif-containing protein 8)
Gene: TRIM8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22262183
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding GO:0016605 - PML body
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 551
+	Hs
		386071 P53_HUMAN (1-393): 0: 619: 100.00		RO52_HUMAN (1-512): 7.11e-85: 273: 13.90
+	Hs
		387560 P53_HUMAN (1-393): 0: 619: 100.00		TRI39_HUMAN (6-526): 1.65e-75: 250: 14.67
+	Hs
		386017 P53_HUMAN (1-393): 0: 619: 100.00		TRI27_HUMAN (1-531): 9.22e-71: 237: 12.63
+	Hs
		262148 P53_HUMAN (1-393): 0: 619: 100.00		TRIM3_HUMAN (10-483): 1.51e-63: 223: 14.96
+	Hs
		387747 P53_HUMAN (1-393): 0: 619: 100.00		TRI33_HUMAN (14-534): 5.05e-61: 220: 14.95
+	Hs
		387458 P53_HUMAN (1-393): 0: 619: 100.00		TRIM2_HUMAN (10-495): 3.74e-61: 216: 14.23
+	Hs
		386725 P53_HUMAN (1-393): 0: 619: 100.00		TRI25_HUMAN (8-365): 1.14e-59: 210: 22.31
+	Hs
		386629 P53_HUMAN (1-393): 0: 619: 100.00		TRI26_HUMAN (1-412): 2.24e-59: 207: 16.39
+	Hs
		170208 P53_HUMAN (1-393): 0: 619: 100.00		TIF1A_HUMAN (14-531): 9.28e-53: 195: 14.06
+	Hs
		387532 P53_HUMAN (1-393): 0: 619: 100.00		TRI45_HUMAN (15-478): 3.95e-53: 191: 15.03
+	Hs
		386838 P53_HUMAN (1-393): 0: 619: 100.00		LIN41_HUMAN (90-439): 3.61e-50: 187: 16.58
+	Hs
		387317 P53_HUMAN (1-393): 0: 619: 100.00		TRI47_HUMAN (13-298): 2.05e-50: 185: 21.28
+	Hs
		387456 P53_HUMAN (1-393): 0: 619: 100.00		TRI31_HUMAN (1-318): 4.16e-42: 158: 19.06