HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: RNF38 (Q9H0F5)
E3 ubiquitin-protein ligase RNF38 (EC 2.3.2.27) (RING finger protein 38) (RING-type E3 ubiquitin transferase RNF38)
Gene: RNF38

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	20308539, 23973461
Identification Methods	affinity chromatography technology, pull down, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 515
+	Hs
		175922 P73_HUMAN (13-362): 2.35e-166: 481: 39.74		RNF38_HUMAN (1-515): 5.32e-114: 348: 100.00
+	Hs
		1327682 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		RNF38_HUMAN (1-515): 5.32e-114: 348: 100.00
+	Hs
		387425 P53_HUMAN (1-393): 0: 619: 100.00		RN126_HUMAN (253-514): 1e-42: 156: 19.29
+	Hs
		387763 P53_HUMAN (1-393): 0: 619: 100.00		RNF6_HUMAN (291-511): 1.99e-32: 133: 22.97
+	Dm
		1213224 Q8IMZ4_DROME (124-325): 1.54e-78: 252: 24.31		Q9VGI6_DROME (206-510): 7.7e-34: 138: 19.16
+	Dm
		1341773 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		Q9VGI6_DROME (206-510): 7.7e-34: 138: 19.16
+	Dm
		1248636 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		Q8SX72_DROME (298-509): 2.79e-30: 127: 41.51