HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: BRPF3 (Q9ULD4)
Bromodomain and PHD finger-containing protein 3
Gene: BRPF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1205
+	Hs
		387506 P53_HUMAN (1-393): 0: 619: 100.00		KDM4C_HUMAN (16-557): 6.88e-81: 289: 17.38
+	Hs
		319103 P53_HUMAN (1-393): 0: 619: 100.00		BRD1_HUMAN (680-1202): 1.71e-77: 279: 28.32
+	Hs
		256930 P53_HUMAN (1-393): 0: 619: 100.00		KDM4A_HUMAN (11-548): 1.04e-73: 268: 16.18
+	Hs
		387566 P53_HUMAN (1-393): 0: 619: 100.00		BRD7_HUMAN (530-726): 6.55e-47: 181: 28.43
+	Hs
		386125 P53_HUMAN (1-393): 0: 619: 100.00		BRD2_HUMAN (546-873): 7.08e-29: 126: 14.63
+	Hs
		386763 P53_HUMAN (1-393): 0: 619: 100.00		BRD3_HUMAN (568-882): 4.36e-28: 124: 12.30
+	Dm
		65195 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		A8DYA3_DROME (10-696): 1.43e-88: 318: 12.82
+	Dm
		1213219 Q8IMZ4_DROME (124-325): 1.54e-78: 252: 24.31		Q9BMQ0_DROME (10-696): 9.98e-85: 306: 12.31