HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	29379164, 17297477
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007265 - Ras protein signal transduction
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 482
+	Hs
		386660 P53_HUMAN (1-393): 0: 619: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		386786 P53_HUMAN (1-393): 0: 619: 100.00		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43
+	Hs
		386717 P53_HUMAN (1-393): 0: 619: 100.00		SAFB2_HUMAN (141-482): 1.89e-41: 160: 14.69
+	Hs
		1073560 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43