Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 25277244
Identification Methods two hybrid, reverse ras recruitment system
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0030018 - Z disc
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 205
Hs

1 892
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Mm
+ Mm
+ Mm
+ Ce

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Last updated: 15 Jul 2024