Protein: COX6
Cytochrome c oxidase subunit 6, mitochondrial (Cytochrome c oxidase polypeptide VI)

Gene: COX6
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: P00427

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005751 - mitochondrial respiratory chain complex IV
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
GO:0016491 - oxidoreductase activity
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

335915

COX2
Cytochrome c oxidase subunit 2

5

0

Small-scale

0.852

High

336021

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

2

1

High-throughput

0.754

High

336104

COX4
Cytochrome c oxidase subunit 4, mitochondrial

2

0

High-throughput

0.716

High

336148

MTC3
Maintenance of telomere capping protein 3, mitochondrial

2

0

High-throughput

0.716

High

335709

COX1
Cytochrome c oxidase subunit 1

5

1

Small-scale

0.699

High

336111

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

3

3

Small-scale

0.640

High

336072

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

1

High-throughput

0.618

High

336110

COX9
Cytochrome c oxidase subunit 9, mitochondrial

3

0

High-throughput

0.616

High

335997

COX3
Cytochrome c oxidase subunit 3

3

0

Small-scale

0.613

High

336123

ADT2
ADP,ATP carrier protein 2

2

1

Small-scale

0.611

High

336151

SHY1
Cytochrome oxidase assembly protein SHY1

2

1

Small-scale

0.611

High

336113

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

3

0

Small-scale

0.606

High

336108

CY1
Cytochrome c1, heme protein, mitochondrial

2

1

High-throughput

0.584

High

336136

MIC60
MICOS complex subunit MIC60

2

0

High-throughput

0.559

High

336146

TOM22
Mitochondrial import receptor subunit TOM22

2

0

High-throughput

0.559

High

336157

COX12
Cytochrome c oxidase subunit 12, mitochondrial

2

0

High-throughput

0.559

High

336152

RCF2
Respiratory supercomplex factor 2, mitochondrial

2

0

Small-scale

0.547

High

336154

ATP9
ATP synthase subunit 9, mitochondrial

2

0

Small-scale

0.547

High

336101

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.479

High

336103

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

336106

VDAC1
Mitochondrial outer membrane protein porin 1

1

1

High-throughput

0.479

High

336109

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

336112

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

3

High-throughput

0.479

High

336132

COX13
Cytochrome c oxidase subunit 13, mitochondrial

1

1

High-throughput

0.479

High

336139

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

1

High-throughput

0.479

High

336140

YTA12
Mitochondrial inner membrane m-AAA protease component YTA12

1

1

High-throughput

0.479

High

336141

PHB1
Prohibitin-1

1

1

High-throughput

0.479

High

336147

PHB2
Prohibitin-2

1

1

High-throughput

0.479

High

336160

YHM2
Citrate/oxoglutarate carrier protein

1

1

High-throughput

0.479

High

336161

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

333348

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.458

High

333398

QCR7
Cytochrome b-c1 complex subunit 7, mitochondrial

1

0

High-throughput

0.458

High

336102

ATP6
ATP synthase subunit a

1

0

Small-scale

0.458

High

336105

COX8
Cytochrome c oxidase subunit 8, mitochondrial

1

0

High-throughput

0.458

High

336107

ATPF
ATP synthase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

336114

QCR8
Cytochrome b-c1 complex subunit 8, mitochondrial

1

0

High-throughput

0.458

High

336115

ATPO
ATP synthase subunit 5, mitochondrial

1

0

High-throughput

0.458

High

336116

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

336118

COX7
Cytochrome c oxidase subunit 7, mitochondrial

1

0

High-throughput

0.458

High

336122

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

336124

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.458

High

336125

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

High-throughput

0.458

High

336126

TOM40
Mitochondrial import receptor subunit TOM40

1

0

High-throughput

0.458

High

336128

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

336129

ATP7
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.458

High

336130

MSS51
Protein MSS51, mitochondrial

1

0

Small-scale

0.458

High

336133

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

0

High-throughput

0.458

High

336134

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

336137

QCR10
Cytochrome b-c1 complex subunit 10, mitochondrial

1

0

High-throughput

0.458

High

336138

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.458

High

336144

COX16
Cytochrome c oxidase assembly protein COX16, mitochondrial

1

0

Small-scale

0.458

High

336145

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.458

High

336149

GEP7
Genetic interactor of prohibitin 7, mitochondrial

1

0

High-throughput

0.458

High

336150

MCY1
Putative mitochondrial cysteine synthase

1

0

High-throughput

0.458

High

336153

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

336156

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.458

High

336162

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.458

High

336163

COA3
Cytochrome c oxidase assembly factor 3, mitochondrial

1

0

Small-scale

0.458

High

336120

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

336127

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.445

High

333473

CYB
Cytochrome b

1

0

Small-scale

0.426

High

336159

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

Small-scale

0.426

High

336158

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

336119

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

336131

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

336142

NOP2
25S rRNA

1

0

High-throughput

0.279

Low

61539

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.249

Low

336117

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

336135

IXR1
Intrastrand cross-link recognition protein

1

0

Small-scale

0.249

Low

336143

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

336155

CTR9
RNA polymerase-associated protein CTR9

1

0

High-throughput

0.249

Low

336121

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024