Interactor 1: CRP (P02741)
C-reactive protein [Cleaved into: C-reactive protein(1-205)]
Gene: CRP

Interactor 2: CO4A (P0C0L4)
Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; Complement C4b-A (Complement C4b-alpha' chain); Complement C4d-A; Complement C4 gamma chain]
Gene: C4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments unassigned3799
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001849 - complement component C1q complex binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006954 - inflammatory response
GO:0045087 - innate immune response
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 224
Hs

1 1744
+ Hs

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Last updated: 11Aug2025