Protein: PTX3
Pentraxin-related protein PTX3 (Pentaxin-related protein PTX3) (Tumor necrosis factor alpha-induced protein 5) (TNF alpha-induced protein 5) (Tumor necrosis factor-inducible gene 14 protein) (TSG-14)

Gene: PTX3
Organism: Homo sapiens
Interactions: 90
UniProt ID: P26022

Gene Ontology (top 5):
GO:0001550 - ovarian cumulus expansion
GO:0001849 - complement component C1q complex binding
GO:0001872 - (1->3)-beta-D-glucan binding
GO:0001878 - response to yeast
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

683712

PTX3
Pentraxin-related protein PTX3

2

8

Small-scale

0.841

High

478451

FGF2
Fibroblast growth factor 2

5

10

Small-scale

0.728

High

683746

NEUFC
Neuferricin

3

3

High-throughput

0.662

High

388496

CRP

1

8

Small-scale

0.618

High

472277

CFAH
Complement factor H

2

6

Small-scale

0.611

High

683768

COL10
Collectin-10

2

5

High-throughput

0.611

High

625984

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

2

1

High-throughput

0.601

High

683724

TNIP1
TNFAIP3-interacting protein 1

2

1

High-throughput

0.601

High

388607

C1QA
Complement C1q subcomponent subunit A

2

5

Small-scale

0.584

High

683725

FCN2
Ficolin-2

2

5

Small-scale

0.584

High

567167

ZNF35
Zinc finger protein 35

2

1

High-throughput

0.549

High

683740

ZN444
Zinc finger protein 444

2

2

High-throughput

0.549

High

683751

NDEL1
Nuclear distribution protein nudE-like 1

2

3

High-throughput

0.549

High

683757

NDE1
Nuclear distribution protein nudE homolog 1

2

3

High-throughput

0.549

High

683723

ITIH4
Inter-alpha-trypsin inhibitor heavy chain H4

1

1

Small-scale

0.536

High

210714

KLK10
Kallikrein-10

1

3

High-throughput

0.536

High

369621

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.536

High

591910

LYAM3
P-selectin

1

6

Small-scale

0.515

High

683721

TSG6
Tumor necrosis factor-inducible gene 6 protein

1

0

Small-scale

0.513

High

683720

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.513

High

683730

SAMD1
Sterile alpha motif domain-containing protein 1

1

0

High-throughput

0.513

High

683739

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.513

High

683760

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.513

High

214097

FGF16
Fibroblast growth factor 16

1

10

Small-scale

0.501

High

240136

FGF17
Fibroblast growth factor 17

1

10

Small-scale

0.501

High

303362

FGF18
Fibroblast growth factor 18

1

10

Small-scale

0.501

High

426940

FGF1
Fibroblast growth factor 1

1

10

Small-scale

0.501

High

551530

FGF5
Fibroblast growth factor 5

1

10

Small-scale

0.501

High

640747

FGF7
Fibroblast growth factor 7

1

10

Small-scale

0.501

High

683718

FGF8
Fibroblast growth factor 8

1

10

Small-scale

0.501

High

683755

FGF22
Fibroblast growth factor 22

1

10

Small-scale

0.501

High

683756

FGF20
Fibroblast growth factor 20

1

10

Small-scale

0.501

High

429331

JUN
Transcription factor Jun

1

4

High-throughput

0.489

High

574006

HXB3
Homeobox protein Hox-B3

1

1

High-throughput

0.489

High

583458

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

2

High-throughput

0.489

High

605238

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

2

High-throughput

0.489

High

683713

NKG2C
NKG2-C type II integral membrane protein

1

3

High-throughput

0.489

High

683727

UBR4
E3 ubiquitin-protein ligase UBR4

1

1

High-throughput

0.489

High

683736

ZN627
Zinc finger protein 627

1

3

High-throughput

0.489

High

683741

ZN709
Zinc finger protein 709

1

1

High-throughput

0.489

High

683748

ZN775
Zinc finger protein 775

1

2

High-throughput

0.489

High

683749

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

2

High-throughput

0.489

High

683750

O52B2
Olfactory receptor 52B2

1

1

High-throughput

0.489

High

141990

FCN1
Ficolin-1

1

5

Small-scale

0.479

High

289305

FCN3
Ficolin-3

1

5

Small-scale

0.479

High

366331

PLMN
Plasminogen

1

3

Small-scale

0.479

High

388695

C1QB
Complement C1q subcomponent subunit B

1

5

Small-scale

0.479

High

388767

C1QC
Complement C1q subcomponent subunit C

1

5

Small-scale

0.479

High

539659

MBL2
Mannose-binding protein C

1

3

Small-scale

0.479

High

683717

MTR1A
Melatonin receptor type 1A

1

3

High-throughput

0.464

High

683716

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

73777

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

5

High-throughput

0.445

High

167437

WNT9A
Protein Wnt-9a

1

2

High-throughput

0.445

High

683765

PRG3
Proteoglycan 3

1

2

High-throughput

0.445

High

683733

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

289930

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.426

High

683714

IL12A
Interleukin-12 subunit alpha

1

0

High-throughput

0.426

High

683743

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.426

High

683761

DKKL1
Dickkopf-like protein 1

1

0

High-throughput

0.426

High

683742

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.407

High

683747

ZN669
Zinc finger protein 669

1

4

High-throughput

0.407

High

683729

TM10B
tRNA methyltransferase 10 homolog B

2

0

High-throughput

0.318

High

601951

ZNF8
Zinc finger protein 8

2

0

High-throughput

0.313

High

134242

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.279

Low

271309

ZBED4
Zinc finger BED domain-containing protein 4

1

0

High-throughput

0.279

Low

302107

CDKL5
Cyclin-dependent kinase-like 5

1

0

High-throughput

0.279

Low

683715

S5A2
3-oxo-5-alpha-steroid 4-dehydrogenase 2

1

0

High-throughput

0.279

Low

683719

PCBP3
Poly(rC)-binding protein 3

1

0

High-throughput

0.279

Low

683731

RBP10
Ran-binding protein 10

1

0

High-throughput

0.279

Low

683732

ZN852
Zinc finger protein 852

1

0

High-throughput

0.279

Low

683735

CENPQ
Centromere protein Q

1

0

High-throughput

0.279

Low

683737

KDM3B
Lysine-specific demethylase 3B

1

0

High-throughput

0.279

Low

683744

OR5C1
Olfactory receptor 5C1

1

0

High-throughput

0.279

Low

683745

THAP3
THAP domain-containing protein 3

1

0

High-throughput

0.279

Low

683753

WDR26
WD repeat-containing protein 26

1

0

High-throughput

0.279

Low

683754

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.279

Low

683759

ZN224
Zinc finger protein 224

1

0

High-throughput

0.279

Low

683762

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.279

Low

683763

POLH
DNA polymerase eta

1

0

High-throughput

0.279

Low

683766

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

0

High-throughput

0.279

Low

683726

AL1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase

1

0

High-throughput

0.269

Low

683722

SQSTM
Sequestosome-1

1

0

High-throughput

0.232

Low

683728

BLT3A
Bridge-like lipid transfer protein family member 3A

1

0

High-throughput

0.232

Low

683734

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.232

Low

683738

KI18B
Kinesin-like protein KIF18B

1

0

High-throughput

0.232

Low

683752

TSN10
Tetraspanin-10

1

0

High-throughput

0.232

Low

683758

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.232

Low

683764

YBOX2
Y-box-binding protein 2

1

0

High-throughput

0.232

Low

683767

STA13
StAR-related lipid transfer protein 13

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025