HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: LUZP1 (Q86V48)
Leucine zipper protein 1
Gene: LUZP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	25277244
Identification Methods	two hybrid, reverse ras recruitment system
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 1076
+	Hs
		148272 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		CTRO_HUMAN (2-458): 4.05e-25: 115: 14.56
+	Hs
		358904 CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42		MYO5C_HUMAN (9-401): 4.77e-16: 86: 16.50
+	Hs
		1356186 HSPB8_HUMAN (1-180): 1.08e-42: 143: 37.17		MYH4_HUMAN (3-532): 3.79e-19: 95.9: 9.52
+	Hs
		522580 HSPB8_HUMAN (1-180): 1.08e-42: 143: 37.17		MYH1_HUMAN (2-471): 1.26e-18: 94.4: 11.21
+	Hs
		61510 HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52		A5YM51_HUMAN (368-712): 2.03e-10: 67.4: 8.57
+	Hs
		528375 HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52		MYH6_HUMAN (333-719): 1.58e-09: 64.7: 6.98
+	Hs
		1356177 HSPB8_HUMAN (1-180): 1.08e-42: 143: 37.17		MYH2_HUMAN (2-278): 5.52e-11: 69.3: 15.11
+	Hs
		528397 HSPB8_HUMAN (1-180): 1.08e-42: 143: 37.17		MYH6_HUMAN (333-719): 1.58e-09: 64.7: 6.98
+	Hs
		528430 HSPB8_HUMAN (1-180): 1.08e-42: 143: 37.17		MYH8_HUMAN (2-263): 8.79e-09: 62: 13.65