HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: MTCH2 (Q9Y6C9)
Mitochondrial carrier homolog 2 (Met-induced mitochondrial protein)
Gene: MTCH2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27684187, 30669930
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 303
+	Mm
		1176491 HSPB2_MOUSE (1-181): 3.51e-43: 144: 33.88		MTCH2_MOUSE (1-303): 9.94e-83: 253: 93.73
+	Hs
		388786 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		S2513_HUMAN (100-302): 1.38e-37: 143: 16.91
+	Hs
		388188 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		ADT3_HUMAN (113-299): 3.27e-29: 114: 14.00
+	Hs
		388147 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		ADT2_HUMAN (113-299): 1.34e-28: 113: 13.50
+	Hs
		274469 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		S2512_HUMAN (4-115): 2e-18: 87.3: 14.29
+	Hs
		358964 CRYAB_HUMAN (18-197): 6.14e-51: 164: 39.44		ADT3_HUMAN (113-299): 3.27e-29: 114: 14.00
+	Dm
		359127 HSP23_DROME (32-203): 9.47e-48: 156: 29.55		ADT_DROME (107-299): 1.54e-27: 110: 12.38
+	Dm
		248272 HSP23_DROME (32-203): 9.47e-48: 156: 29.55		O62526_DROME (117-299): 8.28e-26: 105: 13.78
+	Mm
		851107 HSPB2_MOUSE (1-181): 3.51e-43: 144: 33.88		ADT2_MOUSE (113-299): 6.68e-29: 113: 13.50
+	Hs
		359072 CRYAB_HUMAN (18-197): 6.14e-51: 164: 39.44		S2532_HUMAN (121-280): 5.27e-16: 78.7: 16.77
+	Hs
		358793 CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42		SCMC2_HUMAN (205-302): 1.84e-11: 66.1: 9.18
+	Mm
		1206508 HSPB2_MOUSE (1-181): 3.51e-43: 144: 33.88		S2512_MOUSE (4-115): 1.65e-18: 87.6: 14.29
+	Mm
		1307972 HSPB2_MOUSE (1-181): 3.51e-43: 144: 33.88		MCAT_MOUSE (4-100): 4.27e-11: 64.5: 9.28