HitPredict

Interactor 1: SYTC (P04801)
Threonine--tRNA ligase, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)
Gene: THS1

Interactor 2: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31399574, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005739 - mitochondrion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 734 Sc			1 705
+	Sc
		365516 SYTC_YEAST (1-734): 0: 934: 100.00		HSP82_YEAST (1-705): 0: 968: 95.63
+	Hs
		431553 SYTC_HUMAN (39-727): 0: 859: 56.40		HS90A_HUMAN (4-705): 0: 1013: 60.67
+	Hs
		430844 SYEP_HUMAN (310-732): 1.01e-116: 386: 17.45		HS90A_HUMAN (4-705): 0: 1013: 60.67
+	Sc
		543676 YHI0_YEAST (303-732): 7.54e-113: 358: 15.42		HSC82_YEAST (1-705): 0: 977: 100.00
+	Sc
		366232 YHI0_YEAST (303-732): 7.54e-113: 358: 15.42		HSP82_YEAST (1-705): 0: 968: 95.63
+	Ca
		804483 Q59R20_CANAL (186-732): 1.92e-115: 365: 15.41		HSP90_CANAL (4-705): 0: 953: 82.36
+	Sc
		426419 SYSC_YEAST (195-646): 3.02e-95: 305: 11.11		HSC82_YEAST (1-705): 0: 977: 100.00
+	Sc
		365589 SYSC_YEAST (195-646): 3.02e-95: 305: 11.11		HSP82_YEAST (1-705): 0: 968: 95.63
+	Dm
		659591 SYEP_DROME (311-732): 2.5e-108: 364: 15.70		Q9VAY2_DROME (3-676): 0: 833: 47.09