Protein: CLCB
Clathrin light chain B (Lcb)

Gene: CLCB, CLTB
Organism: Homo sapiens
Interactions: 178
UniProt ID: P09497

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005802 - trans-Golgi network
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

483326

CLH1
Clathrin heavy chain 1

8

7

Small-scale

0.964

High

483312

CLH2
Clathrin heavy chain 2

3

7

High-throughput

0.861

High

271656

HIP1R
Huntingtin-interacting protein 1-related protein

4

6

Small-scale

0.692

High

135876

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

3

3

High-throughput

0.667

High

171658

GAK
Cyclin-G-associated kinase

3

10

High-throughput

0.667

High

174906

SC16A
Protein transport protein Sec16A

3

3

High-throughput

0.667

High

323654

AP2A2
AP-2 complex subunit alpha-2

3

13

High-throughput

0.667

High

344606

AP2A1
AP-2 complex subunit alpha-1

3

13

High-throughput

0.667

High

482994

CLCA
Clathrin light chain A

3

3

High-throughput

0.667

High

483304

EPS15
Epidermal growth factor receptor substrate 15

3

9

High-throughput

0.667

High

483332

PICAL
Phosphatidylinositol-binding clathrin assembly protein

3

7

High-throughput

0.667

High

130908

HIP1
Huntingtin-interacting protein 1

3

6

Small-scale

0.664

High

483335

EPN4
Clathrin interactor 1

3

8

High-throughput

0.656

High

483393

PTN23
Tyrosine-protein phosphatase non-receptor type 23

3

1

Small-scale

0.656

High

483316

SEC13
Protein SEC13 homolog

2

2

High-throughput

0.628

High

483322

AP2B1
AP-2 complex subunit beta

2

11

High-throughput

0.628

High

483380

AP2M1
AP-2 complex subunit mu

2

5

High-throughput

0.628

High

483417

MYO6
Unconventional myosin-VI

2

4

Small-scale

0.619

High

483293

MPRI
Cation-independent mannose-6-phosphate receptor

2

3

High-throughput

0.611

High

483310

NUMB
Protein numb homolog

2

7

High-throughput

0.611

High

483324

DAB2
Disabled homolog 2

2

10

High-throughput

0.611

High

483328

FCHO2
F-BAR domain only protein 2

2

1

High-throughput

0.611

High

483333

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

3

High-throughput

0.611

High

483341

AAK1
AP2-associated protein kinase 1

2

7

High-throughput

0.611

High

483356

AFTIN
Aftiphilin

2

1

High-throughput

0.611

High

483327

OCRL
Inositol polyphosphate 5-phosphatase OCRL

2

4

High-throughput

0.601

High

483395

WNK1
Serine/threonine-protein kinase WNK1

2

6

High-throughput

0.584

High

400164

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

1

High-throughput

0.571

High

483292

HSP7C
Heat shock cognate 71 kDa protein

2

6

High-throughput

0.571

High

483389

WNK3
Serine/threonine-protein kinase WNK3

2

7

High-throughput

0.558

High

483404

BMP2K
BMP-2-inducible protein kinase

2

7

High-throughput

0.558

High

483334

5HT4R
5-hydroxytryptamine receptor 4

1

3

High-throughput

0.541

High

177993

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

3

High-throughput

0.536

High

221829

CHM2A
Charged multivesicular body protein 2a

1

3

High-throughput

0.536

High

225767

AP1G1
AP-1 complex subunit gamma-1

1

13

High-throughput

0.536

High

269937

AUXI
Auxilin

1

3

High-throughput

0.536

High

270759

ROCK2
Rho-associated protein kinase 2

1

2

High-throughput

0.536

High

279105

ULK1
Serine/threonine-protein kinase ULK1

1

2

High-throughput

0.536

High

291745

STK16
Serine/threonine-protein kinase 16

1

7

High-throughput

0.536

High

388939

FINC
Fibronectin

1

1

High-throughput

0.536

High

483294

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

483295

FLNA
Filamin-A

1

1

High-throughput

0.536

High

483298

ARRB2
Beta-arrestin-2

1

2

High-throughput

0.536

High

483299

HSP74
Heat shock 70 kDa protein 4

1

8

High-throughput

0.536

High

483301

MYH9
Myosin-9

1

1

High-throughput

0.536

High

483305

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

High-throughput

0.536

High

483306

CAZA2
F-actin-capping protein subunit alpha-2

1

2

High-throughput

0.536

High

483313

AP2S1
AP-2 complex subunit sigma

1

7

High-throughput

0.536

High

483314

IST1
IST1 homolog

1

1

High-throughput

0.536

High

483319

ARP2
Actin-related protein 2

1

1

High-throughput

0.536

High

483320

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

1

High-throughput

0.536

High

483321

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

5

High-throughput

0.536

High

483330

AP1B1
AP-1 complex subunit beta-1

1

11

High-throughput

0.536

High

483337

STK38
Serine/threonine-protein kinase 38

1

1

High-throughput

0.536

High

483338

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.536

High

483345

TGO1
Transport and Golgi organization protein 1 homolog

1

3

High-throughput

0.536

High

483348

OBSCN
Obscurin

1

2

High-throughput

0.536

High

483350

AP1AR
AP-1 complex-associated regulatory protein

1

1

High-throughput

0.536

High

483353

EDC4
Enhancer of mRNA-decapping protein 4

1

2

High-throughput

0.536

High

483362

DCP2
m7GpppN-mRNA hydrolase

1

1

High-throughput

0.536

High

483365

DCP1B
mRNA-decapping enzyme 1B

1

5

High-throughput

0.536

High

483367

SYNPO
Synaptopodin

1

3

High-throughput

0.536

High

483369

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

4

High-throughput

0.536

High

483372

DEN1A
DENN domain-containing protein 1A

1

1

High-throughput

0.536

High

483374

NU133
Nuclear pore complex protein Nup133

1

1

High-throughput

0.536

High

483375

STON2
Stonin-2

1

5

High-throughput

0.536

High

483377

MY18A
Unconventional myosin-XVIIIa

1

3

High-throughput

0.536

High

483381

EDC3
Enhancer of mRNA-decapping protein 3

1

1

High-throughput

0.536

High

483382

MYO19
Unconventional myosin-XIX

1

5

High-throughput

0.536

High

483385

PRPK
EKC/KEOPS complex subunit TP53RK

1

1

High-throughput

0.536

High

483387

AP1M1
AP-1 complex subunit mu-1

1

5

High-throughput

0.536

High

483388

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

2

High-throughput

0.536

High

483394

CHM4B
Charged multivesicular body protein 4b

1

4

High-throughput

0.536

High

483397

CHM1A
Charged multivesicular body protein 1a

1

6

High-throughput

0.536

High

483398

DCP1A
mRNA-decapping enzyme 1A

1

5

High-throughput

0.536

High

483399

ANLN
Anillin

1

1

High-throughput

0.536

High

483402

PDLI7
PDZ and LIM domain protein 7

1

1

High-throughput

0.536

High

483405

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.536

High

483408

CHMP5
Charged multivesicular body protein 5

1

7

High-throughput

0.536

High

483412

LIMA1
LIM domain and actin-binding protein 1

1

1

High-throughput

0.536

High

483415

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

4

High-throughput

0.536

High

483421

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

3

High-throughput

0.536

High

483422

MARF1
Meiosis regulator and mRNA stability factor 1

1

1

High-throughput

0.536

High

483423

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

3

High-throughput

0.536

High

284270

GEMI
Geminin

1

0

High-throughput

0.513

High

483346

FA83B
Protein FAM83B

1

0

High-throughput

0.513

High

483361

THOC4
THO complex subunit 4

1

0

High-throughput

0.513

High

483420

SMC3
Structural maintenance of chromosomes protein 3

1

0

High-throughput

0.513

High

483307

NEST
Nestin

1

4

High-throughput

0.489

High

483315

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

2

High-throughput

0.489

High

483317

SIK1
Serine/threonine-protein kinase SIK1

1

2

High-throughput

0.489

High

483323

M3K9
Mitogen-activated protein kinase kinase kinase 9

1

2

High-throughput

0.489

High

483340

DREB
Drebrin

1

3

High-throughput

0.489

High

483347

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

4

High-throughput

0.489

High

483355

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

1

High-throughput

0.489

High

483383

ARX
Homeobox protein ARX

1

1

High-throughput

0.489

High

126050

AP3B1
AP-3 complex subunit beta-1

1

12

High-throughput

0.479

High

158762

AP3D1
AP-3 complex subunit delta-1

1

15

Small-scale

0.479

High

169404

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

5

Small-scale

0.479

High

178155

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

215243

TXNL1
Thioredoxin-like protein 1

1

2

High-throughput

0.479

High

215897

SYNJ1
Synaptojanin-1

1

4

High-throughput

0.479

High

269731

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

5

High-throughput

0.479

High

329416

EPN2
Epsin-2

1

10

High-throughput

0.479

High

403758

GCR
Glucocorticoid receptor

1

4

High-throughput

0.479

High

413050

P53
Cellular tumor antigen p53

1

1

Small-scale

0.479

High

483289

CLCB
Clathrin light chain B

1

3

High-throughput

0.479

High

483297

MARK3
MAP/microtubule affinity-regulating kinase 3

1

2

High-throughput

0.479

High

483300

ADA1A
Alpha-1A adrenergic receptor

1

3

Small-scale

0.479

High

483303

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

483309

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

5

Small-scale

0.479

High

483311

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

1

5

High-throughput

0.479

High

483325

VIGLN
Vigilin

1

4

High-throughput

0.479

High

483336

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.479

High

483339

ITSN1
Intersectin-1

1

11

High-throughput

0.479

High

483343

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.479

High

483344

SH319
SH3 domain-containing protein 19

1

9

High-throughput

0.479

High

483352

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

3

High-throughput

0.479

High

483354

SCYL2
SCY1-like protein 2

1

2

High-throughput

0.479

High

483357

DNMBP
Dynamin-binding protein

1

12

High-throughput

0.479

High

483364

SMAP1
Stromal membrane-associated protein 1

1

3

High-throughput

0.479

High

483366

RHG18
Rho GTPase-activating protein 18

1

2

High-throughput

0.479

High

483368

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

483370

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

3

High-throughput

0.479

High

483371

BICD2
Protein bicaudal D homolog 2

1

6

High-throughput

0.479

High

483373

SMAP2
Stromal membrane-associated protein 2

1

3

High-throughput

0.479

High

483376

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

483378

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

483379

VP33A
Vacuolar protein sorting-associated protein 33A

1

1

Small-scale

0.479

High

483392

VP33B
Vacuolar protein sorting-associated protein 33B

1

1

Small-scale

0.479

High

483403

KIF15
Kinesin-like protein KIF15

1

1

High-throughput

0.479

High

483406

GGA3
ADP-ribosylation factor-binding protein GGA3

1

9

High-throughput

0.479

High

483407

ITSN2
Intersectin-2

1

10

High-throughput

0.479

High

483409

HDAC6
Protein deacetylase HDAC6

1

1

High-throughput

0.479

High

483410

TES
Testin

1

3

High-throughput

0.479

High

483414

GGA1
ADP-ribosylation factor-binding protein GGA1

1

8

High-throughput

0.479

High

483416

DP13A
DCC-interacting protein 13-alpha

1

1

High-throughput

0.479

High

483418

SYNRG
Synergin gamma

1

1

High-throughput

0.479

High

483419

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

4

High-throughput

0.479

High

483424

EPN1
Epsin-1

1

8

High-throughput

0.479

High

483302

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

483318

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

483329

ELP6
Elongator complex protein 6

1

0

High-throughput

0.458

High

483331

TRI26
Tripartite motif-containing protein 26

1

0

Small-scale

0.458

High

483342

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

483359

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

483400

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

0

High-throughput

0.458

High

104005

F5GWT4
non-specific serine/threonine protein kinase

1

5

High-throughput

0.445

High

114512

H0YEF7
Phosphatidylinositol binding clathrin assembly protein

1

2

High-throughput

0.445

High

254756

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.445

High

483291

HS71A
Heat shock 70 kDa protein 1A

1

6

High-throughput

0.445

High

483351

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.445

High

483360

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

3

High-throughput

0.445

High

257219

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.438

High

50794

CA226
Uncharacterized protein C1orf226

1

1

High-throughput

0.437

High

81670

EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

1

1

High-throughput

0.437

High

370991

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.437

High

405711

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.437

High

483296

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

2

High-throughput

0.437

High

483349

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.437

High

483358

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

483391

SIK2
Serine/threonine-protein kinase SIK2

1

2

Small-scale

0.437

High

483413

HOOK1
Protein Hook homolog 1

1

5

High-throughput

0.437

High

483425

NUMBL
Numb-like protein

1

9

High-throughput

0.437

High

404630

PRIO
Major prion protein

1

0

High-throughput

0.426

High

483384

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

483390

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

483308

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

287649

KS6A5
Ribosomal protein S6 kinase alpha-5

1

0

High-throughput

0.279

Low

483290

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

483396

TPC
Mitochondrial thiamine pyrophosphate carrier

1

0

High-throughput

0.279

Low

483401

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.279

Low

483411

TCF20
Transcription factor 20

1

0

High-throughput

0.279

Low

105173

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

208011

TTI1
TELO2-interacting protein 1 homolog

1

0

High-throughput

0.249

Low

483363

NAV3
Neuron navigator 3

1

0

High-throughput

0.249

Low

483386

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025