HitPredict

Interactor 1: VDAC1 (P04840)
Mitochondrial outer membrane protein porin 1 (Voltage-dependent anion-selective channel protein 1) (VDAC-1)
Gene: POR1

Interactor 2: ADT2 (P18239)
ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) (Petite colonies protein 9)
Gene: PET9

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	18779372, 37968396, 32051233
Identification Methods	affinity chromatography technology, cross-linking study, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0006915 - apoptotic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 283 Sc			1 318
+	Mm
		851090 VDAC1_MOUSE (3-283): 6.19e-100: 296: 24.74		ADT2_MOUSE (126-317): 8.9e-38: 137: 25.37
+	Hs
		518085 VDAC1_HUMAN (3-283): 5.89e-99: 293: 24.38		ADT1_HUMAN (123-317): 4.58e-38: 138: 24.02
+	Hs
		518249 VDAC1_HUMAN (3-283): 5.89e-99: 293: 24.38		ADT3_HUMAN (122-317): 7.36e-38: 138: 24.39
+	Hs
		397268 VDAC1_HUMAN (3-283): 5.89e-99: 293: 24.38		ADT2_HUMAN (126-317): 1.18e-37: 137: 25.37
+	Sc
		389843 VDAC1_YEAST (1-283): 9.45e-90: 270: 100.00		ADT3_YEAST (5-224): 4.21e-38: 138: 21.82
+	Hs
		601399 VDAC1_HUMAN (3-283): 5.89e-99: 293: 24.38		S2513_HUMAN (17-126): 3.84e-21: 95.7: 18.18
+	Hs
		274465 TOM40_HUMAN (3-279): 8.2e-52: 175: 15.49		S2512_HUMAN (3-126): 4.54e-20: 92.6: 19.36
+	Hs
		330686 TOM40_HUMAN (3-279): 8.2e-52: 175: 15.49		SCMC1_HUMAN (1-116): 6.15e-16: 79.9: 18.80