HitPredict

Interactor 1: RPN2 (P04844)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (RIBIIR) (Ribophorin II) (RPN-II) (Ribophorin-2)
Gene: RPN2

Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 631 Hs			1 1367
+	Hs
		390659 RPN2_HUMAN (1-631): 0: 877: 100.00		INSR_HUMAN (32-1365): 0: 1219: 56.54
+	Rn
		544778 RPN2_RAT (1-631): 0: 852: 93.82		INSR_RAT (20-1365): 0: 1210: 55.45
+	Hs
		390724 RPN2_HUMAN (1-631): 0: 877: 100.00		EPHA8_HUMAN (655-1337): 4.83e-169: 533: 23.87
+	Hs
		390725 RPN2_HUMAN (1-631): 0: 877: 100.00		LTK_HUMAN (989-1319): 5.64e-75: 270: 40.11
+	Hs
		384080 RPN2_HUMAN (1-631): 0: 877: 100.00		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61
+	Hs
		390728 RPN2_HUMAN (1-631): 0: 877: 100.00		UFO_HUMAN (790-1271): 9.27e-68: 249: 32.10
+	Hs
		390913 RPN2_HUMAN (1-631): 0: 877: 100.00		NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16