Protein: ATP7B
Copper-transporting ATPase 2 (EC 7.2.2.8) (Copper pump 2) (Wilson disease-associated protein) [Cleaved into: WND/140 kDa]

Gene: ATP7B
Organism: Homo sapiens
Interactions: 38
UniProt ID: P35670

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005375 - copper ion transmembrane transporter activity
GO:0005507 - copper ion binding
GO:0005524 - ATP binding
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

122319

ATOX1
Copper transport protein ATOX1

5

6

Small-scale

0.930

High

727453

COMD1
COMM domain-containing protein 1

3

1

Small-scale

0.678

High

727447

NRG1
Pro-neuregulin-1, membrane-bound isoform

3

1

High-throughput

0.667

High

49132

TM223
Transmembrane protein 223

2

1

High-throughput

0.628

High

212283

ITM2A
Integral membrane protein 2A

2

10

High-throughput

0.628

High

674778

GRPR
Gastrin-releasing peptide receptor

2

20

High-throughput

0.628

High

727460

CLC2D
C-type lectin domain family 2 member D

2

10

High-throughput

0.628

High

727464

PCDGD
Protocadherin gamma-B1

2

10

High-throughput

0.628

High

727458

MANS1
MANSC domain-containing protein 1

2

0

High-throughput

0.602

High

500737

CLUS
Clusterin

2

2

Small-scale

0.584

High

727443

GLRX1
Glutaredoxin-1

1

2

Small-scale

0.552

High

600743

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

20

High-throughput

0.536

High

727446

X3CL1
Fractalkine

1

2

High-throughput

0.536

High

727449

NTRK3
NT-3 growth factor receptor

1

8

High-throughput

0.536

High

727456

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.536

High

727459

KCMB3
Calcium-activated potassium channel subunit beta-3

1

2

High-throughput

0.536

High

727462

TSN16
Tetraspanin-16

1

13

High-throughput

0.536

High

727465

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.536

High

519403

FCERA
High affinity immunoglobulin epsilon receptor subunit alpha

1

0

High-throughput

0.513

High

167853

NPC1
NPC intracellular cholesterol transporter 1

1

6

High-throughput

0.479

High

205113

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

226690

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

527324

LAMP2
Lysosome-associated membrane glycoprotein 2

1

7

High-throughput

0.479

High

591754

RAB4A
Ras-related protein Rab-4A

1

6

High-throughput

0.479

High

727444

RAB7A
Ras-related protein Rab-7a

1

11

High-throughput

0.479

High

727445

RAB9A
Ras-related protein Rab-9A

1

11

High-throughput

0.479

High

727450

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

727451

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

727452

CXD3
Gap junction delta-3 protein

1

8

High-throughput

0.479

High

727454

RN149
E3 ubiquitin-protein ligase RNF149

1

7

High-throughput

0.479

High

727455

GOGA1
Golgin subfamily A member 1

1

2

High-throughput

0.479

High

727457

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

727463

LAMP3
Lysosome-associated membrane glycoprotein 3

1

7

High-throughput

0.479

High

341191

HPT
Haptoglobin

1

1

Small-scale

0.439

High

164358

TRI66
Tripartite motif-containing protein 66

1

3

High-throughput

0.437

High

636463

DNJB2
DnaJ homolog subfamily B member 2

1

1

High-throughput

0.437

High

727448

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

Small-scale

0.299

High

727461

DCTN4
Dynactin subunit 4

1

0

Small-scale

0.288

High


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Last updated: 15 Jul 2024