HitPredict

Interactor 1: GNAI2 (P04899)
Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI2

Interactor 2: LT4R1 (Q15722)
Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) (G-protein coupled receptor 16) (P2Y purinoceptor 7) (P2Y7)
Gene: LTB4R

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	17139258
Identification Methods	enzymatic study, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	7tm_1~G-alpha
Common GO terms	GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 352
+	Hs
		391305 GNAI2_HUMAN (1-355): 8.42e-180: 504: 100.00		ADRB2_HUMAN (2-324): 1.8e-69: 224: 16.58
+	Hs
		391347 GNAI2_HUMAN (1-355): 8.42e-180: 504: 100.00		OPRD_HUMAN (2-339): 2.73e-69: 222: 24.21
+	Hs
		429011 GNAI1_HUMAN (1-355): 8.33e-178: 498: 87.89		ADRB2_HUMAN (2-324): 1.8e-69: 224: 16.58
+	Hs
		450979 GNAO_HUMAN (1-355): 1.03e-173: 488: 69.30		OPRM_HUMAN (8-346): 7.87e-71: 227: 22.29
+	Hs
		428884 GNAI3_HUMAN (1-355): 1.01e-174: 490: 85.92		ADRB2_HUMAN (2-324): 1.8e-69: 224: 16.58
+	Hs
		450984 GNAO_HUMAN (1-355): 1.03e-173: 488: 69.30		OPRD_HUMAN (2-339): 2.73e-69: 222: 24.21
+	Hs
		686617 GNAQ_HUMAN (1-354): 8.04e-165: 466: 50.42		CCR1_HUMAN (7-337): 4.82e-73: 232: 23.95
+	Hs
		428911 GNAT2_HUMAN (1-355): 1.04e-166: 470: 69.86		ADRB2_HUMAN (2-324): 1.8e-69: 224: 16.58
+	Hs
		674835 GNAQ_HUMAN (1-354): 8.04e-165: 466: 50.42		AGTR1_HUMAN (8-333): 4.21e-67: 217: 25.08
+	Hs
		670446 GNA11_HUMAN (1-354): 2.62e-162: 459: 50.42		CXCR4_HUMAN (6-319): 1.69e-68: 220: 25.16
+	Hs
		686657 GNA13_HUMAN (2-354): 4.58e-153: 437: 39.72		CCR1_HUMAN (7-337): 4.82e-73: 232: 23.95
+	Hs
		895622 GNA13_HUMAN (2-354): 4.58e-153: 437: 39.72		CXCR4_HUMAN (6-319): 1.69e-68: 220: 25.16
+	Hs
		429010 GNAS2_HUMAN (1-355): 1.94e-147: 423: 38.83		ADRB2_HUMAN (2-324): 1.8e-69: 224: 16.58
+	Hs
		391329 GNAI2_HUMAN (1-355): 8.42e-180: 504: 100.00		C5AR1_HUMAN (19-324): 7.11e-31: 121: 31.43
+	Hs
		444666 GNAI3_HUMAN (1-355): 1.01e-174: 490: 85.92		C5AR1_HUMAN (19-324): 7.11e-31: 121: 31.43
+	Hs
		670432 GNA11_HUMAN (1-354): 2.62e-162: 459: 50.42		P2RY1_HUMAN (13-294): 1.59e-24: 104: 27.08