HitPredict

Interactor 1: H2A1B (P04908)
Histone H2A type 1-B/E (Histone H2A.2) (Histone H2A/a) (Histone H2A/m)
Gene: H2AC4

Interactor 2: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27248496
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 732
+	Hs
		470247 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		XRCC5_HUMAN (1-732): 0: 755: 100.00
+	Hs
		524783 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		XRCC5_HUMAN (1-732): 0: 755: 100.00
+	Hs
		470246 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49
+	Hs
		391526 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49
+	Hs
		523498 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49
+	Sc
		392562 H2A2_YEAST (16-128): 1.02e-59: 181: 79.65		KU80_YEAST (8-622): 1.51e-99: 321: 14.03
+	Sc
		392196 H2A1_YEAST (16-127): 9.92e-53: 164: 80.36		KU80_YEAST (8-622): 1.51e-99: 321: 14.03
+	Sc
		392362 H2A2_YEAST (16-128): 1.02e-59: 181: 79.65		KU70_YEAST (8-541): 5.97e-92: 300: 16.73
+	Sc
		392088 H2A1_YEAST (16-127): 9.92e-53: 164: 80.36		KU70_YEAST (8-541): 5.97e-92: 300: 16.73